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The Experimental Study of Glycyrrhiza uralensis on Wound Healing by Antioxidant Effect  

Lee, Yun Kyung (Dept. of Oriental Internal Medicine, Graduate school of Korean Medicine, Daejeon University)
Roh, Seok Sun (Dept. of Oriental Internal Medicine, Graduate school of Korean Medicine, Daejeon University)
Publication Information
Journal of Haehwa Medicine / v.25, no.1, 2016 , pp. 145-153 More about this Journal
Abstract
Objectives : The purpose of this study is to evaluate the wound healing potential of Glycyrrhiza uralensis extract. Methods : Free radical scavenging activity tests for DPPH, peroxynitrite (ONOO) and hydroxyl radical (${\cdot}OH$) and total phenolic contents of Glycyrrhiza uralensis extract were conducted. Tube formation assay was performed using human umbilical vein endothelial cells (HUVECs). Results : The results showed that Glycyrrhiza uralensis extract exerted inhibitory effects on ONOO and ${\cdot}OH$. Tube formation in HUVEC was increase in a dose dependent manner. Conclusions : These results show the potential to promote the wound healing process by Glycyrrhiza uralensis extract.
Keywords
Glycyrrhiza uralensis; wound healing; ONOO; tube formation;
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Times Cited By KSCI : 4  (Citation Analysis)
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