The Plant Pathology Journal

한국식물병리학회 (The Korean Society of Plant Pathology)
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Antifungal Effect of Chitosan as Ca2+ Channel Blocker

  • Lee, Choon Geun (Department of Life Science, College of BioNano, Gachon University) ;
  • Koo, Ja Choon (Division of Science Education and Institute of Fusion Science, Chonbuk National University) ;
  • Park, Jae Kweon (Department of Life Science, College of BioNano, Gachon University)
  • 투고 : 2015.08.17
  • 심사 : 2016.02.15
  • 발행 : 2016.06.01
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초록

The aim of this study was to investigate antifungal activity of a range of different molecular weight (MW) chitosan against Penicillium italicum. Our results demonstrate that the antifungal activity was dependent both the MW and concentration of the chitosan. Among a series of chitosan derived from the hydrolysis of high MW chitosan, the fractions containing various sizes of chitosan ranging from 3 to 15 glucosamine units named as chitooligomers-F2 (CO-F2) was found to show the highest antifungal activity against P. italicum. Furthermore, the effect of CO-F2 toward this fungus was significantly reduced in the presence of $Ca^{2+}$, whereas its effect was recovered by ethylenediaminetetraacetic acid, suggesting that the CO-F2 acts via disruption of $Ca^{2+}$ gradient required for survival of the fungus. Our results suggest that CO-F2 may serve as potential compounds to develop alternatives to synthetic fungicides for the control of the postharvest diseases.

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참고문헌

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