Journal of Veterinary Clinics (한국임상수의학회지)

The Korean Society of Veterinary Clinics (한국임상수의학회)
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Co-existence of Intestinal Adenocarcinoma and Leiomyosarcoma in a Schnauzer Dog

슈나유저 개의 소장에 샘암종과 평활근육종의 동시 발생 1례

  • Yang, Cheol-Ho (Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University) ;
  • Na, Sae-Won (Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University) ;
  • Han, Jae-Ik (Laboratory of Wildlife Diseases, College of Veterinary Medicine, Chonbuk National University) ;
  • Park, Hee-Myung (Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University)
  • 양철호 (건국대학교 수의과대학 내과학교실) ;
  • 나세원 (건국대학교 수의과대학 내과학교실) ;
  • 한재익 (전북대학교 수의과대학 야생동물질병학교실) ;
  • 박희명 (건국대학교 수의과대학 내과학교실)
  • Accepted : 2015.09.22
  • Published : 2016.02.29
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Abstract

A 7-year-old castrated male Schnauzer was presented with melena and inappetence. Laboratory examination revealed mild anemia. Abdominal ultrasonography showed abnormal enlargement of intestinal segment and a oval mass with soft tissue density. After surgical resection of the enlarged intestine including the mass, histopathologic examination showed that the mass was tentatively diagnosed as synchronous occurrence of gland cell- and mesenchymal cell-origin tumors. Subsequently, immunohistochemistry showed positivity to cytokeratin AE1/AE3 in the gland cells and positivity to ${\alpha}-smooth$ muscle-specific actin, but negative expression of c-Kit, suggesting the co-existence of adenocarcinoma and leiomyosarcoma. Follow-up examination after 3-year of the surgery confirmed that the dog remained healthy and did not show recurrence of the tumors.

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References

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