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http://dx.doi.org/10.17555/jvc.2016.02.33.1.43

Co-existence of Intestinal Adenocarcinoma and Leiomyosarcoma in a Schnauzer Dog  

Yang, Cheol-Ho (Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University)
Na, Sae-Won (Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University)
Han, Jae-Ik (Laboratory of Wildlife Diseases, College of Veterinary Medicine, Chonbuk National University)
Park, Hee-Myung (Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University)
Publication Information
Journal of Veterinary Clinics / v.33, no.1, 2016 , pp. 43-47 More about this Journal
Abstract
A 7-year-old castrated male Schnauzer was presented with melena and inappetence. Laboratory examination revealed mild anemia. Abdominal ultrasonography showed abnormal enlargement of intestinal segment and a oval mass with soft tissue density. After surgical resection of the enlarged intestine including the mass, histopathologic examination showed that the mass was tentatively diagnosed as synchronous occurrence of gland cell- and mesenchymal cell-origin tumors. Subsequently, immunohistochemistry showed positivity to cytokeratin AE1/AE3 in the gland cells and positivity to ${\alpha}-smooth$ muscle-specific actin, but negative expression of c-Kit, suggesting the co-existence of adenocarcinoma and leiomyosarcoma. Follow-up examination after 3-year of the surgery confirmed that the dog remained healthy and did not show recurrence of the tumors.
Keywords
dog; small intestine; adenocarcinoma; leiomyosarcoma; synchronous tumor;
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