Journal of the Society of Cosmetic Scientists of Korea (대한화장품학회지)

Society of Cosmetic Scientists of Korea (대한화장품학회)
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Effect of Mixing Route and Temperature on Formation of Nanoemulsions

나노에멀젼 형성에서의 혼합 경로와 온도의 영향

  • 조완구 (전주대학교 의과학대학 바이오기능성식품학과) ;
  • 김은희 (전주대학교 의과학대학 바이오기능성식품학과) ;
  • 장선일 ((주)아토큐앤에이 기업부설연구소) ;
  • 조병옥 ((주)아토큐앤에이 기업부설연구소)
  • Received : 2016.10.19
  • Accepted : 2016.12.07
  • Published : 2016.12.30
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Abstract

In this work, we compared the emulsion states having the same composition of liquid paraffin/ Span 80-Tween 80/ pure water and the different mixing paths and temperatures. Routes reaching the final composition in three component phase diagram were composed of three different ways. The average particle size of the emulsion prepared from the different mixing routes showed a significant difference and decreased as the mixing temperature was increased. However, the mixing route affected more in the size of the emulsions than mixing temperature.

본 연구에서는 동일한 농도의 유동파라핀/ Span 80-Tween 80/ 정제수로 구성되는 조성물을 혼합 경로와 온도에 따라 형성되는 에멀젼 상태를 비교하였다. 3성분계도상에서 최종 조성에 이르는 혼합경로는 세 가지로 구성하였다. 혼합 경로에 따라서 제조된 에멀젼의 평균 입자크기는 큰 차이를 보였으며 제조 온도가 증가함에 따라서도 에멀젼의 입자크기가 감소하였다. 그러나 혼합 온도보다는 혼합 경로에 따른 영향이 더욱 컸다.

Keywords

References

  1. E. H. Kim and W. G. Cho, Stable liquid paraffin-in-water nanoemulsions prepared by phase inversion composition method, J. Soc. Cosmet. Sci. Kor., 40(2), 133 (2014).
  2. N. Y. Yukuyama, D. D. M. Ghislene, T. J. A. Pinto, and N. A. Bon-Chacra, Nanoemulsion: process selection and application in cosmetics - a review, Int. J. Cos. Sci., 38(1), 13 (2016). https://doi.org/10.1111/ics.12260
  3. C. Solans, P. Izquierdo, J. Nolla, N. Azemar, and M. J. Garcia-Celma, Nano-emulsions, Curr. Opin. Colloid Inter. Sci., 10(3-4), 102 (2005). https://doi.org/10.1016/j.cocis.2005.06.004
  4. C. Solans, I. Sole, A. Fernandez-Arteaga, J. Nolla, N. Azemar, J. M. Gutierrez, A. Maestro, C. Gonzalez, and C. M. Pey, Surfactant Science Series, Ed. Hidalgo-Alvarez Roque, 146, 457, Taylor and Francis Group (2010).
  5. J. M. Gutierrez, C. Gonzalez, A. Maestro, I. Sole, C. M. Pey, and J. Nolla, Nano-emulsions: new applications and optimization of their preparation, Curr. Opin. Colloid Interf. Sci., 13(4), 245 (2008). https://doi.org/10.1016/j.cocis.2008.01.005
  6. M. Antonietti and K. Landfester, Polyreactions in miniemulsions, Prog. Polym. Sci., 27(4), 689 (2002). https://doi.org/10.1016/S0079-6700(01)00051-X
  7. J. M. Asua, Miniemulsion polymerization, Prog. Polym. Sci., 27(7), 1283 (2002). https://doi.org/10.1016/S0079-6700(02)00010-2
  8. T. Delmas, H. Piraux, A. C. Couffin, I. Texier, F. Vinet, P. Poulin, M. E. Cates, and J. Bibette, How to prepare and stabilize very small nanoemulsions, Langmuir, 27(5), 1683 (2011). https://doi.org/10.1021/la104221q
  9. F. Ganachaud and J. L. Katz, Nanoparticles and nanocapsules created using the ouzo effect: spontaneous emulsification as an alternative to ultrasonic and high-shear devices, Chem. Phys. Chem., 6(2), 209 (2005). https://doi.org/10.1002/cphc.200400527
  10. A. Forgiarini, J. Esquena, C. Gonzalez, and C. Solans, Formation of nano-emulsions by low-energy emulsification methods at constant temperature, Langmuir, 17(7), 2076 (2001). https://doi.org/10.1021/la001362n
  11. W. Liu, D. Sun, C. Li, Q. Liu, and J. Xu, Formation and stability of paraffin oil-in-water nano-emulsions prepared by the emulsion inversion point method, J. Colloid Interf. Sci., 303(2), 57 (2006).
  12. O. Sonneville-Aubrun, D. Babayan, D. Bordeaux, P. Lindner, G. Rata, and B. Cabane, Phase transition pathways for the production of 100 nm oil-in-water emulsions, Phys. Chem. Chem. Phys., 11(1), 101 (2009). https://doi.org/10.1039/B813502A
  13. D. Morales, J. M. Gutierrez, M. J. Garcia-Celma, and C. Solans, A study of the relation between bicontinuous microemulsions and oil/water nanoemulsion formation, Langmuir, 19(18), 7196 (2003). https://doi.org/10.1021/la0300737
  14. P. Izquierdo, J. Esquena, T. F. Tadros, J. C. Dederen, J. Feng, M. J. Garcia-Celma, N. Azemar, and C. Solans, Phase behavior and nano-emulsion formation by the phase inversion temperature method, Langmuir, 20(16), 6594 (2004). https://doi.org/10.1021/la049566h
  15. E. H. Kim and W. G. Cho, Nano-emulsion formed with phospholipid-nonionic surfactant mixtures and its stability, J. Soc. Cosmet. Sci. Kor., 40(3), 221 (2014).
  16. C. Qian and D. J. McClements, Formation of nanoemulsions stabilized by model food-grade emulsifiers using high-pressure homogenization: Factors affecting particle size, Food Hydrocoll., 25(5), 1000 (2011). https://doi.org/10.1016/j.foodhyd.2010.09.017
  17. P. Fernandez, V. Andre, J. Rieger, and A. Kuhnle, Nano-emulsion formation by emulsion phase inversion, Colloids Surf. A, Physicochem. Eng. Asp., 251(1), 53 (2004). https://doi.org/10.1016/j.colsurfa.2004.09.029