A Case of Basal Cell Adenocarcinoma with Neck Metastasis in the Parotid Gland

경부전이를 동반하여 이하선에 발생한 기저세포선암 1예

  • Park, Jae Hong (Department of Otorhinolaryngology-Head and Neck Surgery, Soonchunhyang University College of Medicine) ;
  • Kim, Won Shik (Department of Otorhinolaryngology, Yonsei University College of Medicine) ;
  • Byeon, Hyung Kwon (Department of Otorhinolaryngology, Yonsei University College of Medicine) ;
  • Hong, Hyun Jun (Department of Otorhinolaryngology, Catholic Kwandong University College of Medicine) ;
  • Jung, Hae Yoen (Department of Pathology, Soonchunhyang University College of Medicine) ;
  • Ban, Myung Jin (Department of Otorhinolaryngology-Head and Neck Surgery, Soonchunhyang University College of Medicine)
  • 박재홍 (순천향대학교 의과대학 천안병원 이비인후과-두경부외과) ;
  • 김원식 (연세대학교 의과대학 이비인후과학교실) ;
  • 변형권 (연세대학교 의과대학 이비인후과학교실) ;
  • 홍현준 (가톨릭 관동대학교 국제성모병원 이비인후과) ;
  • 정혜연 (순천향대학교 의과대학 천안병원 병리과학교실) ;
  • 반명진 (순천향대학교 의과대학 천안병원 이비인후과-두경부외과)
  • Received : 2015.03.15
  • Accepted : 2015.04.29
  • Published : 2015.05.30

Abstract

Basal cell adenocarcinoma is a extremely rare low grade malignancy of the salivary gland. It is composed of basaloid cells with dark cell, light cells and pale cytoplasm which shows infiltrative growth pattern into adjacent glandular parenchyme. The pathophysiology of basal cell adenocarcinoma is not well known. First hypothesis is a malignant transformation of the monomorphic adenoma and second one is a de novo origin. Metastasis to the regional lymph nodes is rare. Recently, we have experienced a case of basal cell adenocarcinoma with neck metastasis after previous superficial parotidectomy. For this reason we report this rare case discussed with references.

Keywords

References

  1. Cuthbertson DW, Raol N, Hicks J, Green L, Parke R. Minor Salivary Gland Basal Cell Adenocarcinoma. A Systematic Review and Report of a New Case. JAMA Otolaryngol Head Neck Surg. 2015;141(3):276-283. https://doi.org/10.1001/jamaoto.2014.3344
  2. Batsakis JG, Brannon RB, Sciubba JJ. Monomorphic adenomas of major salivary glands: A study of 96 tumors. Clin Otolaryngol. 1981;16:129.
  3. Ellis GL, Gnepp DR. Unusual salivary gland tumors. In: Pathology of the head and neck, (ed Gnepp DR): New York, Churchill Livinstone; 1988. p.617-623.
  4. Muller S, Barnes L. Basal cell adenocarcinoma of the salivary glands: Report of seven cases and review of the literature. Cancer. 1996;78(12):2471-2477. https://doi.org/10.1002/(SICI)1097-0142(19961215)78:12<2471::AID-CNCR4>3.0.CO;2-N
  5. Barnes L, Eveson JW, Reichart P, Sidransky D,eds. Pathology and genetics of tumors of the head and neck: World Health Organization Classification of Tumors. Vol 9. Lyon: IARC Press; 2005.
  6. Hirsch, Miles, Dierks. BCAC of the Parotid Gland J Oral Maxillofac Surg; 2007.
  7. Luna MA, Batsakis JG, Tortoledo ME. Carcinomas ex monomorphic adenoma of the salivary glands. J Laryngol Otol. 1989;103:756. https://doi.org/10.1017/S0022215100109995
  8. Ellis GL, Wiscovitch JG. Basal cell adenocarcinomas of the major salivary glands. Oral Surg Oral Med Oral Pathol. 1990;69:461. https://doi.org/10.1016/0030-4220(90)90380-B
  9. Farrell T, Chang YL. Basal cell adenocarcinoma of minor salivary glands. Arch Pathol Lab Med. 2007;131(10):1602-1604.