A Case of Mantle Cell Lymphoma Involving the Parotid Gland and Upper Neck

이하선과 상경부에 동시 발생한 외투세포 림프종 1예

  • Kwak, Seul Gi (Department of Otolaryngology-Head and Neck Surgery, Veterans Health Service Medical Center) ;
  • Kim, Choon Dong (Department of Otolaryngology-Head and Neck Surgery, Veterans Health Service Medical Center) ;
  • Kim, Yoon Jung (Department of Pathology, Veterans Health Service Medical Center) ;
  • Kim, Seung Woo (Department of Otolaryngology-Head and Neck Surgery, Veterans Health Service Medical Center)
  • 곽슬기 (중앙보훈병원 이비인후과) ;
  • 김춘동 (중앙보훈병원 이비인후과) ;
  • 김윤정 (중앙보훈병원 병리과) ;
  • 김승우 (중앙보훈병원 이비인후과)
  • Received : 2015.03.04
  • Accepted : 2015.04.30
  • Published : 2015.05.30

Abstract

The Mantle cell lymphoma(MCL) is a relatively rare subtype of malignant lymphoma characterized by chromosomal translocation t(11 ; 14)(q13 ; q32), positive response for CD5, and nuclear cyclin D1. It is account for an estimated 3-6% of all non-Hodgkin's lymphoma. The involvement of extra-nodal site is not uncommon, whereas salivary glands are rarely affected. It is more commonly occurred in men and old age and approximately 75% of cases are diagnosed with advanced stage. It is usually characterized by an aggressive clinical course, and the prognosis is poorer than other type of head and neck lymphoma. We recently encountered a 69-year-old female with mass in parotid tail and upper neck, and it was diagnosed as mantle cell lymphoma. We report the unique case with a review of literature.

Keywords

References

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