Journal of Digital Convergence (디지털융복합연구)

The Society of Digital Policy and Management (한국디지털정책학회)
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Convergence Study for Relationship Between Cholesterol Level on Serum and Depression in Korean Adults

우리나라 성인에서 혈청 콜레스테롤 수준과 우울증의 연관성에 대한 융복합적 연구

  • Lee, Tae-Yong (Dept. of Preventive Medicine, School of Medicine, Chungnam National University) ;
  • Choi, Se-Mook (Dept. of Clinical Pathology, Jinju Health College)
  • 이태용 (충남대학교 의학전문대학원 예방의학교실) ;
  • 최세묵 (진주보건대학교 임상병리과)
  • Received : 2015.02.23
  • Accepted : 2015.05.20
  • Published : 2015.05.28
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Abstract

In order to examine the relationship between cholesterol level on serum and depression in Korean adults, this study used data of the fourth Korea National Health and Nutrition Examination Survey (KNHANES). 834 persons with depressive symptoms were selected as an index group and 3,317 persons without depressive symptoms as a control group, and odds ratios were calculated by multivariate logistic regression. As a result, odds ratio of depressive symptoms was higher in low LDL group (OR=6.435, 95% CI; 2,358-17.557) than in high LDL group adjusted after monthly income, marital status, period of education, occupation, smoking status, and physical activity. Etiopathogenic mechanism must be found by convergent study in the future.

혈청 콜레스테롤 수준과 우울증의 연관성을 파악하고자 제4기 국민건강영양조사의 설문조사와 검사자료에서 우울증상군 834명과 대조군 3,317명을 추출하여 다변량 로지스틱 회귀분석으로 교차비를 계산하였다. 분석 결과 우울증상은 가족 월수입, 결혼상태, 교육기간, 직업, 흡연상태, 신체활동을 보정한 상태에서 저밀도지단백이 낮을 때(기준 높음) 교차비가 6.435배(95% CI)로 유의하게 높았다. 결론적으로 낮은 저밀도지단백은 우울 증상을 높일 위험이 높다는 것이 밝혀졌다. 그러나 아직 콜레스테롤에 의한 우울 기전이 아직 밝혀지지 않았기 때문에 추후 다양한 분야의 융복합 연구를 통하여 이를 밝힐 필요가 있다.

Keywords

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