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Development of Inductive and Capacitive Type Intraocular Pressure (IOP) Sensor to Improve Sensitivity and Minimize Size

민감도 향상과 센서 소형화를 위한 자기 및 용량형 안압센서의 개발

  • Jang, Cheol In (Center for Biomicrosystems, Korea Institute of Science and Technology (KIST)) ;
  • Shin, Kyeong-Sik (Center for Biomicrosystems, Korea Institute of Science and Technology (KIST)) ;
  • Yun, Kwang-Seok (Department of Electronic Engineering, Sogang University) ;
  • Kim, Yong Woo (Department of Ophthalmology, Seoul National University Hospital) ;
  • Kang, Ji Yoon (Center for Biomicrosystems, Korea Institute of Science and Technology (KIST)) ;
  • Lee, Soo Hyun (Center for Biomicrosystems, Korea Institute of Science and Technology (KIST))
  • 장철인 (한국과학기술연구원 바이오 마이크로시스템 연구단) ;
  • 신경식 (한국과학기술연구원 바이오 마이크로시스템 연구단) ;
  • 윤광석 (서강대학교 전자공학과) ;
  • 김용우 (서울대학교병원 안과의국) ;
  • 강지윤 (한국과학기술연구원 바이오 마이크로시스템 연구단) ;
  • 이수현 (한국과학기술연구원 바이오 마이크로시스템 연구단)
  • Received : 2014.10.30
  • Accepted : 2014.11.28
  • Published : 2014.11.30

Abstract

We had presented an inductive type intraocular pressure sensor (L-sensor) in previous work. The distance between a micro coil and a ferrite on the membrane was modulated by pressure, and as a result the inductance and resonant frequency were changed. However, L-sensor has some problems to implant in eyes. First problem is low sensitivity. When L-sensor was implanted in rabbit's eyes, resonant frequency of L-sensor was very hard to detect. Second problem is biocompatibility. Size of L-sensor is $6{\times}7{\times}1.2mm$. When L-sensor was implanted in the eyes, it caused the inflammation. Therefore, this study suggests an inductive and capacitive type IOP sensor (LCsensor). The sensitivity of the LC-sensor 27.3 kHz/mmHg under 60mmHg. It is much larger than 14 kHz/mmHg of the L-sensor. And the size of LC-sensor is 47% smaller than L-sensor. After 2 weeks from the implantation of LC-sensor into rabbit eyes, we measured the changes of resonant frequency of LC-sensor according to increased IOP by Balanced Salt Solution (BSS) injection. As a result, the sensitivity of LC-sensor in in vivo test is 25 kHz/mmHg. That is similar to the sensitivity of in vitro test.

Keywords

References

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