한국안광학회지 (Journal of Korean Ophthalmic Optics Society)

한국안광학회 (The Korean Ophthalmic Optics Society)
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친수성 소프트 콘택트렌즈의 물리적 특성에 미치는 습윤성 재료의 영향

Influence of Wetting Agents on Physical Properties of Soft Contact Lens

  • 이민제 (세한대학교 안경광학과) ;
  • 성아영 (세한대학교 안경광학과) ;
  • 김태훈 (백석대학교 안경광학과)
  • Lee, Min-Jae (Dept. of Ophthalmic Optics, Sehan University) ;
  • Sung, A-Young (Dept. of Ophthalmic Optics, Sehan University) ;
  • Kim, Tae-Hun (Dept. of Visual Optics, Baekseok University)
  • 투고 : 2014.01.30
  • 심사 : 2014.03.15
  • 발행 : 2014.03.31
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초록

목적: 본 연구는 glycerin과 PVP(polyvinylpyrrolidone)을 각각 첨가제로 사용하였을 때 친수성 콘택트렌즈의 물성 변화를 평가하였다. 방법: Glycerin과 PVP(polyvinylpyrrolidone)를 각각 첨가제로 사용하여 교차결합제인 EGDMA (ethylene glycol dimethacrylate) 기본적인 모노머인 HEMA(2-hydroxyethyl methacrylate)와 그리고 개시제인 AIBN(azobisisobutyronitrile)을 기본 조합으로 하여 공중합하였다. 결과: 생성된 고분자의 물리적 특성을 측정한 결과 PVP(polyvinylpyrrolidone)의 경우, 굴절률은 1.4382~1.4288로, 인장강도는 0.3446~0.2542 kgf로 각각 감소하였으며, 접촉각은 21.44% 감소되고 함수율은 13.49% 증가하였다. 또한 glycerin의 경우, 굴절률 1.4330~1.4328로, 인장강도는 0.2974~0.2854 kgf로, 함수율은 35.58~36.53%로 큰 변화를 보이지 않았으며, 접촉각의 경우 37.64%가 감소되었다. 결론: 본 실험결과로 볼 때, 생성된 공중합체는 고 습윤성 안 의료용 렌즈 재료로 사용이 가능하며, 또한 glycerin을 첨가제로 사용하였을 때, 함수율과 굴절률의 변화를 최소화시킴과 동시에 친수성 렌즈의 습윤성을 증가시켰다.

Purpose: The physical and optical characteristics of hydrophilic contact lens polymerized with addition of glycerin and PVP(polyvinylpyrrolidone) in the basic hydrogel contact lens material were evaluated. Methods: This study used glycerin and PVP(polyvinylpyrrolidone) with the cross-linker EGDMA (ethylene glycol dimethacrylate), HEMA (2-hydroxyethyl methacrylate) and the initiator AIBN (azobisisobutyronitrile) for copolymerization. Results: Measurements of the physical characteristics of the copolymerized material including PVP(polyvinylpyrrolidone) showed the refractive index of 1.4382~1.4288, tensile strength of 0.3446~2542 kgf and water content and contact angle of sample showed the increase of 13.49% and decrease of 21.44% independently. And also, the physical characteristics of the copolymerized material including glycerin showed the refractive index of 1.4330~1.4328, tensile strength of 0.2974~0.2854 kgf, water content 35.58~36.53% and contact angle of sample showed the decrease of 37.64%. Conclusions: Based on the results of this study, the produced copolymers is suitable for conventional lens with high wettability. Also, glycerin minimized the changes of water content and refractive index at the same time, increased the wettability of the hydrogel lens materials.

키워드

참고문헌

  1. Kim TH, Sung AY. Physical Characterization and Contact Lens Application of Polymer Produced with Propylene Glycol Additive. J Korean Chem Soc. 2010;54(1):105-109. https://doi.org/10.5012/jkcs.2010.54.01.105
  2. Cho SA, Kim TH, Sung AY. Polymerization and Characterization of Ophthalmic Polymer Containing Glycerol dimethacrylate with High Wettability. J Korean Chem Soc. 2011;55(2):283-289. https://doi.org/10.5012/jkcs.2011.55.2.283
  3. Kim DH, Kim TH, Sung AY. Study on the Strength and Surface Characteristics of Ophthalmic Copolymer with Glycol Group. J Korean Chem Soc. 2012;56(2):297-302. https://doi.org/10.5012/jkcs.2012.56.2.297
  4. Ye KH, Kim TH, Sung AY. Study on the water content variation of contact lens with silicone type. Korean J Vis Sci. 2008;10(1):63-70.
  5. Masnick KB, Holden BA. A Study of water content and parametric variations of hydrophilc contact lenses. Aust J Optom. 1972;55(12):481-487.
  6. Tranoudis I, Efron N. Parameter stability of soft contact lenses made from different materials. Contact Lens & Anterior Eye. 2004;27(3):115-131. https://doi.org/10.1016/j.clae.2004.03.001
  7. Yazdani SS, Gonzalez R. Anaerobic fermentation of glycerol: a path to economic viability for the biofuels industry. Current Opinion in Biotechnology. 2007;18(3):213-219. https://doi.org/10.1016/j.copbio.2007.05.002
  8. Kanaze FI, Kokkalou E, Niopas I, Barmpalexis P, Georgarakis E, Bikiaris E. Dissolution rate and stability study of flavanone aglycones, naringenin and hesperetin, by drug delivery systems based on polyvinylpyrrolidone (PVP) nanodispersions. Drug Development and Industrial Pharmacy. 2007;36(3):292-301.
  9. Han IS, lim YM, Kwon HJ, Park JS, No YC Preparation and Characterization of Polyvinylpyrrolidone/$\kappa$-Carrageenan/ Hxanediol Hydrogel by Gamma-ray Irradiation. Polymer (Korea). 2011;35(1):13-16.
  10. Chun YS. Current concepts and therapeutic management of Dry Eye. J Korean Med Assoc. 2007;50(9):842-847. https://doi.org/10.5124/jkma.2007.50.9.842

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