Radiation Preparation and Characterization of Antimicrobial Hydrogels

방사선 이용 항균성 천연추출물 함유 하이드로겔 제조 및 특성 연구

  • Gwon, Hui-Jeong (Research Division for Industry & Environment, Korea Atomic Energy Research Institute) ;
  • Park, Eun Ji (Quegenbiotech, Co., Ltd) ;
  • Choi, Jong-Bae (Research Division for Industry & Environment, Korea Atomic Energy Research Institute) ;
  • Lim, Jong-Young (Research Division for Industry & Environment, Korea Atomic Energy Research Institute) ;
  • Jeong, Jin-Oh (Research Division for Industry & Environment, Korea Atomic Energy Research Institute) ;
  • Shin, Young Min (Research Division for Industry & Environment, Korea Atomic Energy Research Institute) ;
  • Jeong, Sung In (Research Division for Industry & Environment, Korea Atomic Energy Research Institute) ;
  • Park, Jong-Seok (Research Division for Industry & Environment, Korea Atomic Energy Research Institute) ;
  • Lim, Youn-Mook (Research Division for Industry & Environment, Korea Atomic Energy Research Institute)
  • 권희정 (한국원자력연구원 첨단방사선연구소 공업환경연구부) ;
  • 박은지 ((주)큐젠바이오텍) ;
  • 최종배 (한국원자력연구원 첨단방사선연구소 공업환경연구부) ;
  • 임종영 (한국원자력연구원 첨단방사선연구소 공업환경연구부) ;
  • 정진오 (한국원자력연구원 첨단방사선연구소 공업환경연구부) ;
  • 신영민 (한국원자력연구원 첨단방사선연구소 공업환경연구부) ;
  • 정성린 (한국원자력연구원 첨단방사선연구소 공업환경연구부) ;
  • 박종석 (한국원자력연구원 첨단방사선연구소 공업환경연구부) ;
  • 임윤묵 (한국원자력연구원 첨단방사선연구소 공업환경연구부)
  • Received : 2013.07.07
  • Accepted : 2013.08.01
  • Published : 2013.03.31

Abstract

Taraxacum platycarpum (TP) has been used for years without restriction on usual dose for its non-toxic nature and nonexistence of the side effects. To develop antimicrobial hydrogel, poly (vinylalcohol) (PVA) hydrogels containing the aqueous extracted TP as an antimicrobial agent were prepared by using gamma-rays irradiation. The antimicrobial activities of the TP hydrogels were tested against Staphylococcus aureus and Staphylococcus epidermidis by disc diffusion method. The inhibition zones (IZ) of the TP extracts and TP hydrogels against S. aureus were 16 mm and 20 mm and against S. epidermidis was 10 mm and 13 mm, respectively. In conclusion, the TP hydrogel that has an excellent antimicrobial activity was proved to be a valuable material for functional skin care.

Keywords

Acknowledgement

Supported by : 한국과학재단