Transactions of the Korean Society of Mechanical Engineers B (대한기계학회논문집B)

The Korean Society of Mechanical Engineers (대한기계학회)
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Performance Improvement of Polymer Deposition System by Nozzle Guide and Its Application to Washer Scaffold Fabrication

노즐 가이드를 적용한 폴리머 적층 시스템의 Washer Scaffold 제작을 위한 성능 개선

  • 사민우 (국립안동대학교 기계공학과) ;
  • 김종영 (국립안동대학교 기계공학과)
  • Received : 2012.03.23
  • Accepted : 2012.11.30
  • Published : 2013.03.01
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Abstract

Rapid prototyping was used to design and develop a three-dimensional (3D) scaffold for tissue engineering application. In this study, the nozzle guide (TB-CP-HN, MUSASHI ENGINEERING, INC., JAPAN) used with the syringe of the polymer deposition system (PDS) was evaluated by measuring the scaffold line width and height. 3D scaffolds were fabricated using a biodegradable polymer called poly-caprolactone (PCL). The PCL polymer can be deposited from the needle of a syringe using a 200-${\mu}m$ precision nozzle, at a pressure of 600 kPa and temperature of $125^{\circ}C$. The advantages and improvements in this nozzle guide were addressed through washer scaffold fabrication. Overall, this research indicated that the fabrication of a complex-shaped scaffold using an enhanced polymer deposition system may have potential for tissue engineering.

쾌속조형기술을 이용한 3차원 형상의 인공지지체가 조직공학 적용을 위해 개발되고 제작되었다. 본 연구에서는 폴리머 적층 시스템을 이용한 스캐폴드 제작에 있어 시린지 노즐 부분에 노즐 가이드를 장착하여 폴리머 적층 폭과 높이 실험을 수행하였다. 이 때 인공지지체 제작을 위한 생체재료로 폴리카프로락톤이 사용되었다. 폴리머 적층 공정 조건으로는 600 kPa의 공압과 $125^{\circ}C$의 온도가 이용되었다. 성공적인 와셔 인공지지체 제작을 통해 폴리머 적층 시스템에 적용된 노즐 가이드의 성능이 검증되었다. 결론적으로, 향상된 폴리머 적층 시스템을 이용함으로써 복잡한 형상의 조직공학용 3 차원 인공지지체를 제작할 수 있을 것으로 기대된다.

Keywords

References

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