Bulletin of the Korean Chemical Society

Korean Chemical Society (대한화학회)
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Rhodamine Based Fluorescent Chemosensors for Hg2+ and its Biological Application

  • Choi, Ji-Young (Department of Chemistry and Nano Science and Department of Bioinspired Science (WCU), Ewha Womans University) ;
  • Kim, Wan-Tae (Anyang Foreign Language High School) ;
  • Yoon, Ju-Young (Department of Chemistry and Nano Science and Department of Bioinspired Science (WCU), Ewha Womans University)
  • Received : 2012.04.01
  • Accepted : 2012.04.21
  • Published : 2012.07.20
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Abstract

Two new chemosensors, rhodamine 6G derivative bearing hydroxyethyl group (1) and rhodamine base derivative bearing 15-crown-5 group (2) were synthesized and their sensing behaviors toward various metal ions were investigated by UV/Vis and fluorescence spectroscopies. Addition of $Hg^{2+}$ ion to a $CH_3CN$ solution of 1 and 2 gave visual color changes as well as fluorescent OFF-ON observations. Selectivity and sensitivity of 1 towards $Hg^{2+}$ are excellent enough to detect micromolar level of $Hg^{2+}$ ion, even in equeous media and biological sample (HeLa cell).

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References

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