DOI QR코드

DOI QR Code

안구건조증환자 11례의 한·양방 병용치료에 대한 임상보고

Eastern and Western Combined Medical Treatments on 11 Patients with Dry Eye Syndrome

  • 이동진 (부산대학교한방병원 한방안이비인후피부과) ;
  • 황보민 (부산대학교한방병원 한방안이비인후피부과) ;
  • 서형식 (부산대학교한방병원 한방안이비인후피부과) ;
  • 김수진 (부산대학교병원 안과) ;
  • 이종수 (부산대학교병원 안과)
  • Lee, Dong-Jin (Dept. of Ophthalmology, Otolaryngology and Dermatology Korean Medicine Hospital of Pusan National University) ;
  • HwangBo, Min (Dept. of Ophthalmology, Otolaryngology and Dermatology Korean Medicine Hospital of Pusan National University) ;
  • Seo, Hyung-Sik (Dept. of Ophthalmology, Otolaryngology and Dermatology Korean Medicine Hospital of Pusan National University) ;
  • Kim, Soo-Jin (Dept. of Ophthalmology Hospital of Pusan National University) ;
  • Lee, Jong-Soo (Dept. of Ophthalmology Hospital of Pusan National University)
  • 투고 : 2012.04.16
  • 심사 : 2012.05.11
  • 발행 : 2012.05.25

초록

Objective : The endpoint of this trial is to verify therapeutical availability of conventional western eyedrops combined with acupuncture treatment by means of BUT(tear film break-up time), Schirmer's test, which have been considered to be typical methods for diagnosing dry eye syndrome. Methods : The subjects of this trial included the outpatients who had been diagnosed with dry eye syndrome in Pusan national university hospital and underwent acupuncture treatment from March 2011 to April 2011. They received acupuncture treatment once a week, three times while constantly using Restasis or artificial tears. We collated and analyzed the outcome data of Schirmer's test and BUT conducted at the beginning of this trial and three times more after each acupuncture treatments. Acupoints, such as, Chanjuk(BL2), Eoryo, Sajukgong(TE23), Taeyang, Sabaek(ST2), limited around both eyes were selected based on their clinical effects referring to medical books. Results : 1. From BUT test results, Restasis and acupuncture combined group showed statistically significant difference, however, artificial tears and acupuncture combined group showed difference only between before and after the treatment, which is not statistically significant. 2. From Schirmer's test results, Restasis and acupuncture combined group showed statistically significant difference, however, artificial tears and acupuncture combined group showed difference only between before and after the treatment, which is not statistically significant. 3. The average duration of treatment was statistically 16.3 days for Restasis and acupuncture combined group. Conclusions : Combination of acupuncture and Restasis for dry eye syndrome can shorten the duration of treatment. Therefore, clinical benefit is expected to be worth.

키워드

참고문헌

  1. Lemp MA. Report of the National Eye Institute/Industry workshop on Clinical Trials in Dry Eyes. CLAO J. 1995;21(4):221-32.
  2. Perry HD, Donnenfeld ED. Dry eye diagnosis and management in 2004. Curr Opin Ophthalmology. 2004;15:299-304. https://doi.org/10.1097/00055735-200408000-00004
  3. Smith RE. The tear film complex pathogenesis and emerging therapies for dry eyes. Cornea. 2005;24:1-7. https://doi.org/10.1097/01.ico.0000141486.56931.9b
  4. Balaram M, Schaumberg DA, Dana RD. Efficacy and tolerability outcome after punctual occlusion with silicone plug in dry eye syndrome. Am J Ophthalmol. 2001;131:31-6.
  5. Behrens A, Doyle JJ, Stern L, Chuck RS, et al. Dysfunctional tear syndrome: a Delphi approach to treatment recommendations. Cornea. 2006;25(8):900-7. https://doi.org/10.1097/01.ico.0000214802.40313.fa
  6. Law SK, Li T. Acupuncture for glaucoma. Cochrance Database Syst Rev. 2007;CD006030.
  7. Lee MS, Shin BC, Choi TY, Ernst E. Acupuncture for treating dry eye : a systematic review. Acta Ophthalmol. 2010.
  8. Liu Y, Yang G, Long YS, Jiao Y. Observation on therapeutic effect of acupuncture for treatment of optic atrophy. Zhongguo Zhen Jiu. 2009;29:714-6.
  9. Shin MS, Kim JI, Lee MS, et al. Acupuncture for treating dry eye : a randomized placebo-controlled trial. Acta Ophthalmologica. 2010;88:328-33. https://doi.org/10.1111/j.1755-3768.2010.02027.x
  10. Tseng KL, Liu HJ, Tso KY, et al. A clinical study of acupuncture and Silver spike point electro-therapy for dry eye syndrome. The american Journal of Chinese Medicine. 2006;34:197-206. https://doi.org/10.1142/S0192415X0600376X
  11. Uchino M, Schaumberg DA, Dogru M, Uchino Y, et al. Prevalence of dry eye disease among Japanese visual display terminal users. Ophthalmology. 2008;115(11): 1982-8. https://doi.org/10.1016/j.ophtha.2008.06.022
  12. Definition and Classification Subcommittee of the International Dry Eye Workshop (2007): The definition and Classification Subcommittee of the International Dry Eye Workshop(2007). Ocul Surf. 2007;5:75-92. https://doi.org/10.1016/S1542-0124(12)70081-2
  13. Stern ME, Beuerman RW, Fox RI, Gao J, Mircheff AK, Pflugfelder SC, The pathology of dry eye: the interaction between the ocular surface and lacrimal gland. Cornea. 1998;17:584-9. https://doi.org/10.1097/00003226-199811000-00002
  14. Lee JS, Yoon TJ, Kim KH. Clinical Effect of Restasis Eye Drops in Mild Dry Eye Syndrome. J Korean Ophthalmol Soc. 2009;50(10):1489-94. https://doi.org/10.3341/jkos.2009.50.10.1489
  15. Her J, Yu SI, Seo SG. Clinical Effects of Various Antiinflammatory Therapies in Dry Eye Syndrome. J Korean Ophthalmol Soc. 2006;47(12):1901-10.
  16. Choi EH, Jeon JH, Kim YI. Clinical Observation on 3 Cases of Dry Eye Syndrome. J Korean Acupuncture & Moxibustion Soc. 2007;24(4):237-45.
  17. Lee CW, Lee EK, Jeon JH, Kim JH, Kim YI, Kim JI. Effects of Acupuncture Therapy on Dry Eye Syndrome: 43 Case Series. J Korean Acupuncture & Moxibustion Soc. 2010;27(6):85-94.

피인용 문헌

  1. 한방안이비인후피부과학회지에 게재된 안과 관련 논문에 관한 고찰 vol.27, pp.2, 2014, https://doi.org/10.6114/jkood.2014.27.2.014
  2. 한의학 융합 연구와 관련된 국내외 연구 동향 고찰 vol.29, pp.4, 2012, https://doi.org/10.15188/kjopp.2015.08.29.4.313
  3. 한의학 학술지에 게재된 안구건조증에 대한 논문 고찰 vol.31, pp.2, 2017, https://doi.org/10.15188/kjopp.2017.04.31.2.94
  4. 한, 양방 협진치료에 대한 연구 경향 분석: 국내 논문을 대상으로 vol.28, pp.1, 2012, https://doi.org/10.18325/jkmr.2018.28.1.53
  5. 안구건조증에 대한 Rg3진센약침의 임상적 효과 6례 보고 vol.39, pp.5, 2012, https://doi.org/10.22246/jikm.2018.39.5.929
  6. 건성안 증후군 환자에서 인목탕의 유효성 평가를 위한 후향적 관찰연구 vol.27, pp.4, 2019, https://doi.org/10.14374/hfs.2019.27.4.285