참고문헌
- Medzhitov, R. 2008. Origin and physiological roles of inflammation. Nature 454: 428-435.
- Barton, G. M. 2008. A calculated response: control of inflammation by the innate immune system. J. Clin. Invest. 118: 413-420. https://doi.org/10.1172/JCI34431
- Seo, S. K., J. H. Choi, Y. H. Kim, W. J. Kang, H. Y. Park, J. H. Suh, B. K. Choi, D. S. Vinay, and B. S. Kwon. 2004. 4-1BB-mediated immunotherapy of rheumatoid arthritis. Nat. Med. 10: 1088-1094.
- Olofsson, P. S., L. A. Söderström, D. Wågsäter, Y. Sheikine, P. Ocaya, F. Lang, C. Rabu, L. Chen, M. Rudling, P. Aukrust, U. Hedin, G. Paulsson-Berne, A. Sirsjö, and G. K. Hansson. 2008. CD137 is expressed in human atherosclerosis and promotes development of plaque inflammation in hypercholesterolemic mice. Circulation 117: 1292-1301. https://doi.org/10.1161/CIRCULATIONAHA.107.699173
- Jeon, H. J., J. H. Choi, I. H. Jung, J. G. Park, M. R. Lee, M. N. Lee, B. Kim, J. Y. Yoo, S. J. Jeong, D. Y. Kim, J. E. Park, H. Y. Park, K. Kwack, B. K. Choi, B. S. Kwon, and G. T. Oh. 2010. CD137 (4-1BB) deficiency reduces atherosclerosis in hyperlipidemic mice. Circulation 121: 1124-1133. https://doi.org/10.1161/CIRCULATIONAHA.109.882704
- Dumitriu, I. E., P. Baruah, C. J. Finlayson, I. M. Loftus, R. F. Antunes, P. Lim, N. Bunce, and J, C, Kaski. 2012. High levels of costimulatory receptors OX40 and 4-1BB characterize CD4+CD28null T cells in patients with acute coronary syndrome. Circ. Res. 110: 857-869.
- Haga, T., J. Suzuki, H. Kosuge, M. Ogawa, H. Saiki, G. Haraguchi, Y. Maejima, M. Isobe, and T. Uede. 2009. Attenuation of experimental autoimmune myocarditis by blocking T cell activation through 4-1BB pathway. J. Mol. Cell. Cardiol. 46: 719-727. https://doi.org/10.1016/j.yjmcc.2009.02.003
- Seo, S. K., H. Y. Park, J. H. Choi, W. Y. Kim, Y. H. Kim, H. W. Jung, B. Kwon, H. W. Lee, and B. S. Kwon. 2003. Blocking 4-1BB/4-1BB ligand interactions prevents herpetic stromal keratitis. J. Immunol. 171: 576-583.
- Wang, J., Z. Guo, Y. Dong, O. Kim, J. Hart, A. Adams, C. P. Larsen, R. S. Mittler, and K. A. Newell. 2003. Role of 4-1BB in allograft rejection mediated by CD8+ T cells. Am. J. Transplant. 3: 543-551.
- Cho, H. R., B. Kwon, H. Yagita, S. La, E. A. Lee, J. E. Kim, H. Akiba, J. Kim, J. H. Suh, D. S. Vinay, S. A. Ju, B. S. Kim, R. S. Mittler, K. Okumura, and B. S. Kwon. 2004. Blockade of 4-1BB (CD137)/4-1BB ligand interactions increases allograft survival. Transpl. Int. 17: 351-361.
- Cheung, C. T., T. A. Deisher, H. Luo, B. Yanagawa, S. Bonigut, A. Samra, H. Zhao, E. K. Walker, and B. M. McManus. 2007. Neutralizing anti-4-1BBL treatment improves cardiac function in viral myocarditis. Lab. Invest. 87: 651-661.
- Kim, W., J. Kim, D. Jung, H. Kim, H. J. Choi, H. R. Cho, and B. Kwon. 2009. Induction of lethal graft-versus-host disease by anti-CD137 monoclonal antibody in mice prone to chronic graft-versus-host disease. Biol. Blood Marrow Transplant. 15: 306-314.
- Blazar, B. R., B. S. Kwon, A. Panoskaltsis-Mortari, K. B. Kwak, J. J. Peschon, and P. A. Taylor. 2001. Ligation of 4-1BB (CDw137) regulates graft-versus-host disease, graft-versus- leukemia, and graft rejection in allogeneic bone marrow transplant recipients. J. Immunol. 166: 3174-3183.
- Croft, M. 2009. The role of TNF superfamily members in T-cell function and diseases. Nat. Rev. Immunol. 9: 271-285.
- Kim, D. H., W. S. Chang, Y. S. Lee, K. A. Lee, Y. K. Kim, B. S. Kwon, and C. Y. Kang. 2008. 4-1BB engagement costimulates NKT cell activation and exacerbates NKT cell ligand- induced airway hyperresponsiveness and inflammation. J. Immunol. 180: 2062-2068.
- Vinay, D. S., B. K. Choi, J. S. Bae, W. Y. Kim, B. M. Gebhardt, and B. S. Kwon. 2004. CD137-deficient mice have reduced NK/NKT cell numbers and function, are resistant to lipopolysaccharide-induced shock syndromes, and have lower IL-4 responses. J. Immunol. 173: 4218-4229.
- Lee, S. C., S. A. Ju, H. N. Pack, S. K. Heo, J. H. Suh, S. M. Park, B. K. Choi, B. S. Kwon, B. S. Kim. 2005. 4-1BB (CD137) is required for rapid clearance of Listeria monocytogenes infection. Infect. Immun. 73: 5144-5151.
- Heinisch, I. V., I. Daigle, B. Knöpfli, and H. U. Simon. 2000. CD137 activation abrogates granulocyte-macrophage colony- stimulating factor-mediated anti-apoptosis in neutrophils. Eur. J. Immunol. 30: 3441-3446.
- Nishimoto, H., S. W. Lee, H. Hong, K. G. Potter, M. Maeda-Yamamoto, T. Kinoshita, Y. Kawakami, R. S. Mittler, B. S. Kwon, C. F. Ware, M. Croft, and T. Kawakami. 2005. Costimulation of mast cells by 4-1BB, a member of the tumor necrosis factor receptor superfamily, with the high-affinity IgE receptor. Blood 106: 4241-4248.
- Heinisch, I. V., C. Bizer, W. Volgger, and H. U. Simon. 2001. Functional CD137 receptors are expressed by eosinophils from patients with IgE-mediated allergic responses but not by eosinophils from patients with non-IgE-mediated eosinophilic disorders. J. Allergy Clin. Immunol. 108: 21-28.
- Futagawa, T., H. Akiba, T. Kodama, K. Takeda, Y. Hosoda, H. Yagita, and K. Okumura. 2002. Expression and function of 4-1BB and 4-1BB ligand on murine dendritic cells. Int. Immunol. 14: 275-286.
- Wilcox, R. A., A. I. Chapoval, K. S. Gorski, M. Otsuji, T. Shin, D. B. Flies, K. Tamada, R. S. Mittler, H. Tsuchiya, D. M. Pardoll, and L. Chen. 2002. Cutting edge: Expression of functional CD137 receptor by dendritic cells. J. Immunol. 168: 4262-4267.
- Drenkard, D., F. M. Becke, J. Langstein, T. Spruss, L. A. Kunz-Schughart, T. E. Tan, Y. C. Lim, and H. Schwarz. 2007. CD137 is expressed on blood vessel walls at sites of inflammation and enhances monocyte migratory activity. FASEB J. 21: 456-463.
- Kim, C. S., J. G. Kim, B. J. Lee, M. S. Choi, H. S. Choi, T. Kawada, K. U. Lee, and R. Yu. 2011. Deficiency for costimulatory receptor 4-1BB protects against obesity-induced inflammation and metabolic disorders. Diabetes 60: 3159-3168.
- Lee, S. W., Y. Park, S. Y. Eun, S. Madireddi, H. Cheroutre,and M. Croft. 2012. Cutting edge: 4-1BB controls regulatory activity in dendritic cells through promoting optimal expression of retinal dehydrogenase. J. Immunol. 189: 2697- 2701.
- Kim, J., W. Kim, H. J. Kim, S. Park, H. A. Kim, D. Jung, H. J. Choi, S. J. Park, R. S. Mittler, H. R. Cho, and B. Kwon. 2012. Superscript CD25+CD4+Foxp3+ regulatory T cells primed by anti-CD137 mAbs inhibit graft-versus-host disease. Biol. Blood Marrow Transplant. 18: 44-54.
- Saiki, H., J. Suzuki, H. Kosuge, G. Haraguchi, T. Ishihara, T. Haga, Y. Maejima, M. Isobe, and T. Uede. 2008. Blockade of the 4-1BB pathway attenuates graft arterial disease in cardiac allografts. Int. Heart J. 49: 105-118.
- Kwon, B. 2009. CD137-CD137 Ligand Interactions in Inflammation. Immune Netw. 9: 84-89.
- Shao, Z. and H. Schwarz. 2011. CD137 ligand, a member of the tumor necrosis factor family, regulates immune responses via reverse signal transduction. J. Leukoc. Biol. 89: 21-29.
- Kim, D. K., S. C. Lee, and H. W. Lee. 2009. CD137 ligand- mediated reverse signals increase cell viability and cytokine expression in murine myeloid cells: involvement of mTOR/p70S6 kinase and Akt. Eur. J. Immunol. 39: 2617-2628.
- Kang, Y. J., S. O. Kim, S. Shimada, M. Otsuka, A. Seit-Nebi, B. S. Kwon, T. H. Watts, and J. Han. 2007. Cell surface 4-1BBL mediates sequential signaling pathways 'downstream' of TLR and is required for sustained TNF production in macrophages. Nat. Immunol. 8: 601-609.
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Kim, J. D., E. A. Lee, N. N. Quang, H. R. Cho, and B. Kwon. 2011. Recombinant TAT-CD137 ligand cytoplasmic domain fusion protein induces the production of IL-6 and TNF-
$\alpha$ in peritoneal macrophages. Immune Netw. 11: 216-222. - Kim, H. J., J. S. Lee, J. D. Kim, H. J. Cha, A. Kim, S. K. Lee, S. C. Lee, B. S. Kwon, R. S. Mittler, H. R. Cho, and B. Kwon. 2012. Reverse signaling through the costimulatory ligand CD137L in epithelial cells is essential for natural killer cell-mediated acute tissue inflammation. Proc. Natl. Acad. Sci. USA 109: E13-E22.
- Park, S. J., H. J. Kim, J. S. Lee, H. R. Cho, and B. Kwon. 2012. Reverse signaling through the co-stimulatory ligand, CD137L, as a critical mediator of sterile inflammation. Mol. Cells 33: 533-537.
피인용 문헌
- Importance of reverse signaling of the TNF superfamily in immune regulation vol.9, pp.4, 2012, https://doi.org/10.1586/eci.13.14
- CD137-inducing factors from T cells and macrophages accelerate the destabilization of atherosclerotic plaques in hyperlipidemic mice vol.28, pp.11, 2014, https://doi.org/10.1096/fj.14-253732
- Substrate-dependent gene regulation of self-assembled human MSC spheroids on chitosan membranes vol.15, pp.1, 2012, https://doi.org/10.1186/1471-2164-15-10
- Integration of the Innate and Adaptive Immunity by CD137-CD137L Bidirectional Signals: Implications in Allograft Rejection vol.28, pp.3, 2012, https://doi.org/10.4285/jkstn.2014.28.3.113
- Tumor-Unrelated CD4 T Cell Help Augments CD134 plus CD137 Dual Costimulation Tumor Therapy vol.195, pp.12, 2012, https://doi.org/10.4049/jimmunol.1502032
- Enhancing the safety of antibody-based immunomodulatory cancer therapy without compromising therapeutic benefit: Can we have our cake and eat it too? vol.16, pp.5, 2016, https://doi.org/10.1517/14712598.2016.1152256
- Genetic Aberrations Associated with Photodynamic Therapy in Colorectal Cancer Cells vol.20, pp.13, 2012, https://doi.org/10.3390/ijms20133254
- The Micro-Immunotherapy Medicine 2LEID Exhibits an Immunostimulant Effect by Boosting Both Innate and Adaptive Immune Responses vol.23, pp.1, 2022, https://doi.org/10.3390/ijms23010110