The Korean Journal of Medicine

The Korean Association of Internal Medicine (대한내과학회)
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Localized Uterine Recurrence of Hepatocellular Carcinoma 4 Years after Curative Resection

간세포암 완치 절제 4년 후 자궁에만 국소적으로 재발한 간세포암 1예

  • Lee, Sang-Jin (Department of Internal Medicine, Ulsan University Hospital, University of Ulsan College of Medicine) ;
  • Shin, Jung-Woo (Department of Internal Medicine, Ulsan University Hospital, University of Ulsan College of Medicine) ;
  • Park, Neung-Hwa (Department of Internal Medicine, Ulsan University Hospital, University of Ulsan College of Medicine) ;
  • Nah, Yang-Won (Department of Surgery, Ulsan University Hospital, University of Ulsan College of Medicine) ;
  • Yoo, Hang-Jo (Department of Obstetrics and Gynecology, Ulsan University Hospital, University of Ulsan College of Medicine) ;
  • Jung, Yoong-Ki (Department of Radiology, Ulsan University Hospital, University of Ulsan College of Medicine) ;
  • Choi, Hye-Jeong (Department of Pathology, Ulsan University Hospital, University of Ulsan College of Medicine)
  • 이상진 (울산대학교 의과대학 울산대학교병원 내과) ;
  • 신정우 (울산대학교 의과대학 울산대학교병원 내과) ;
  • 박능화 (울산대학교 의과대학 울산대학교병원 내과) ;
  • 나양원 (울산대학교 의과대학 울산대학교병원 외과) ;
  • 유항조 (울산대학교 의과대학 울산대학교병원 산부인과) ;
  • 정융기 (울산대학교 의과대학 울산대학교병원 영상의학과) ;
  • 최혜정 (울산대학교 의과대학 울산대학교병원 병리과)
  • Published : 2012.05.01
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Abstract

Extrahepatic metastasis of hepatocellular carcinoma (HCC) can be found in various organs, but metastasis to the female genital tract is extremely rare. A 48-year-old woman who had undergone curative left lobectomy for small HCC 4 years earlier was admitted because of sequential alpha-fetoprotein elevation. Upon abdominal MRI and hepatic angiography, no evidence of HCC recurrence was found in the remnant liver. However, a positron emission tomography CT scan showed a hypermetabolic lesion in the uterine fundus, which was revealed as metastatic HCC after total hysterectomy. This is, to our knowledge, the first documented case of metastatic uterine tumor that originated from HCC without intrahepatic recurrence.

원발성 간세포암이 난소전이가 없이 자궁으로 전이하는 경우는 매우 드물다. 저자들은 4년 전 조기 간세포암으로 완치 절제술을 시행 받았던 환자에서 AFP의 점차적인 상승으로 재발을 진단하기 위한 검사에서 간내 간세포암의 재발 없이 자궁에만 국소적으로 재발한 전이성 간세포암 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다.

Keywords

References

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