수차례 재발한 다발성 부신경절종 1예

A Case of Multiple Paraganglioma Presenting as Recurrent Tumor Nermerous Times

  • 이석희 (충북대학교 의과대학 이비인후과학교실) ;
  • 선민진 (충북대학교 의과대학 이비인후과학교실) ;
  • 최미숙 (충북대학교 의과대학 이비인후과학교실) ;
  • 이동욱 (충북대학교 의과대학 이비인후과학교실)
  • Lee, Seok-Hee (Department of Otolaryngology-Head and Neck Surgery, College of Medicine, Chungbuk National University) ;
  • Sun, Min-Jin (Department of Otolaryngology-Head and Neck Surgery, College of Medicine, Chungbuk National University) ;
  • Choi, Mi-Suk (Department of Otolaryngology-Head and Neck Surgery, College of Medicine, Chungbuk National University) ;
  • Lee, Dong-Wook (Department of Otolaryngology-Head and Neck Surgery, College of Medicine, Chungbuk National University)
  • 발행 : 2011.05.27

초록

Paraganglioma is a relatively rare, generally benign and slow growing tumor arising from widely distributed paraganglionic tissue thought to originate from the neural crest. In the head and neck region, paraganglionic tissue is distributed in the superior and inferior paraganglia such as the carotid body, the vagal body, and the jugulotympanic region. Approximately 10% of patients with paraganglioma have a family history of such tumors. Multiple lesions can be found in 26% of patients with family history. It is important to distinguish between paraganglioma and atypical carcinoid tumor and medullary thyroid cancer. This can be done with histopathologic evaluation and immunohistochemical markers. Complete excision is recommended for the treatment of this tumor. Paraganglioma is particularly aggressive and rapid recurrence of paraganglioma is common after local resection. We present a case of malignant paraganglioma in the neck which recurred 2 months after local resection. We suppose that radiation therpay could be the last option for the treatment in this clinical setting.

키워드

참고문헌

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