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중간 세로칸 악성 곁신경절종

A Case of Middle Mediastinal Malignant Paraganglioma

  • 박성범 (성균관대학교 의과대학 내과학교실) ;
  • 박실비아 (성균관대학교 의과대학 내과학교실) ;
  • 방선하 (성균관대학교 의과대학 내과학교실) ;
  • 김은경 (성균관대학교 의과대학 내과학교실) ;
  • 전경만 (성균관대학교 의과대학 내과학교실) ;
  • 고원중 (성균관대학교 의과대학 내과학교실) ;
  • 서지영 (성균관대학교 의과대학 내과학교실) ;
  • 정만표 (성균관대학교 의과대학 내과학교실) ;
  • 김호중 (성균관대학교 의과대학 내과학교실) ;
  • 권오정 (성균관대학교 의과대학 내과학교실) ;
  • 고영혜 (삼성서울병원 병리학교실) ;
  • 엄상원 (성균관대학교 의과대학 내과학교실)
  • Park, Sung-Bum (Department of Medicine, Sungkyunkwan University School of Medicine) ;
  • Park, Silvia (Department of Medicine, Sungkyunkwan University School of Medicine) ;
  • Bang, Sun-Ha (Department of Medicine, Sungkyunkwan University School of Medicine) ;
  • Kim, Eun-Kyung (Department of Medicine, Sungkyunkwan University School of Medicine) ;
  • Jeon, Kyeong-Man (Department of Medicine, Sungkyunkwan University School of Medicine) ;
  • Koh, Won-Jung (Department of Medicine, Sungkyunkwan University School of Medicine) ;
  • Suh, Gee-Young (Department of Medicine, Sungkyunkwan University School of Medicine) ;
  • Chung, Man-Pyo (Department of Medicine, Sungkyunkwan University School of Medicine) ;
  • Kim, Ho-Joong (Department of Medicine, Sungkyunkwan University School of Medicine) ;
  • Kwon, O-Jung (Department of Medicine, Sungkyunkwan University School of Medicine) ;
  • Go, Young-Hyeh (Department of Pathology, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Um, Sang-Won (Department of Medicine, Sungkyunkwan University School of Medicine)
  • 투고 : 2010.09.17
  • 심사 : 2010.10.13
  • 발행 : 2011.02.28

초록

Pheochromocytomas are neuroendocrine tumors of chromaffin cell that originate in the paraganglia of the adrenal medulla. Approximately 10% of pheochromocytomas are found in the extra-adrenal paraganglia and are called paragangliomas. However, cases of middle mediastinal paragangliomas are very rare. In this case, the patient presented with a voice change and a headache. A middle mediastinal soft tissue mass with marked enhancement was detected on computed tomography of the chest. The 24-hour urine catecholamine level was markedly elevated. The middle mediastinal mass was biopsied via mediastinoscopy and the resulting immunohistochemical staining was compatible with a diagnosis of middle mediastinal paraganglioma. The mass was resected surgically and the symptoms were relieved.

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참고문헌

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