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http://dx.doi.org/10.4046/trd.2011.70.2.165

A Case of Middle Mediastinal Malignant Paraganglioma  

Park, Sung-Bum (Department of Medicine, Sungkyunkwan University School of Medicine)
Park, Silvia (Department of Medicine, Sungkyunkwan University School of Medicine)
Bang, Sun-Ha (Department of Medicine, Sungkyunkwan University School of Medicine)
Kim, Eun-Kyung (Department of Medicine, Sungkyunkwan University School of Medicine)
Jeon, Kyeong-Man (Department of Medicine, Sungkyunkwan University School of Medicine)
Koh, Won-Jung (Department of Medicine, Sungkyunkwan University School of Medicine)
Suh, Gee-Young (Department of Medicine, Sungkyunkwan University School of Medicine)
Chung, Man-Pyo (Department of Medicine, Sungkyunkwan University School of Medicine)
Kim, Ho-Joong (Department of Medicine, Sungkyunkwan University School of Medicine)
Kwon, O-Jung (Department of Medicine, Sungkyunkwan University School of Medicine)
Go, Young-Hyeh (Department of Pathology, Samsung Medical Center, Sungkyunkwan University School of Medicine)
Um, Sang-Won (Department of Medicine, Sungkyunkwan University School of Medicine)
Publication Information
Tuberculosis and Respiratory Diseases / v.70, no.2, 2011 , pp. 165-169 More about this Journal
Abstract
Pheochromocytomas are neuroendocrine tumors of chromaffin cell that originate in the paraganglia of the adrenal medulla. Approximately 10% of pheochromocytomas are found in the extra-adrenal paraganglia and are called paragangliomas. However, cases of middle mediastinal paragangliomas are very rare. In this case, the patient presented with a voice change and a headache. A middle mediastinal soft tissue mass with marked enhancement was detected on computed tomography of the chest. The 24-hour urine catecholamine level was markedly elevated. The middle mediastinal mass was biopsied via mediastinoscopy and the resulting immunohistochemical staining was compatible with a diagnosis of middle mediastinal paraganglioma. The mass was resected surgically and the symptoms were relieved.
Keywords
Paraganglioma; Mediastinum; Neoplasms;
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