한국응용과학기술학회지 (Journal of the Korean Applied Science and Technology)

  • 제28권3호
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  • Pages.267-272
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  • 2011
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  • 1225-9098(pISSN)
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  • 2288-1069(eISSN)
한국응용과학기술학회 (The Korean Society of Applied Science and Technology)
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밀리타리스 동충하초($Cordyceps$ $Militalis$)열수 추출물이 스트렙토 조토신으로 유발된 당뇨 흰쥐의 항 당뇨 대사에 미치는 영향

Antidiabetic Metabolism Effect on the water Extract of $Cordyceps$ $Militalis$ in Streptozotocin-Induced Diabetic Rats

  • 김옥경 (대진대학교 자연과학대학 식품영양학과)
  • Kim, Ok-Kyung (Department of Food and Nutrition, Dae Jin University)
  • 투고 : 2011.07.26
  • 심사 : 2011.09.29
  • 발행 : 2011.09.30
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초록

This study was carried to investigate the antidiabetic metabolism effect of water extract $Cordyceps$ $Militalis$(C.M.) in Streptozotocin(STZ) induced diabetic rats. Diabetes were induced by intravenous injection of STZ at a dose of 42mg/kg,b.w. dissolved in citrate buffer. The water extract of C.M. was orally administrated once a day for 7 days at a dose of 500mg/kg,b.w(body weight). or 1,000mg/kg.b.w. The content serum glucose was significantly decreased in C.M. treated group compared to the those of STZ-control group. The content of hepatic glycogen and activities of glucose-6-phosphate dehydrogenase(G-6-PDH), glucokinase(GK) were significantly increased, but activity of glucose-6-phoshatase(G-6-Pase) was significantly decreased in C.M. treated group compared to the those of STZ-control group. These results indicated that water extract of C.M. would have antidiabetic metabolism effect in STZ-induced diabetic rats.

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참고문헌

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