A Case Study on Drug Prescription for Vascular Dementia in Western and Oriental Medicine

혈관성치매에 대한 한.양방 치료약물의 처방 사례연구

  • Choi, Seong-Hun (Department of Anatomy and Histology, College of Oriental Medicine, Daeggu Haany University) ;
  • Cheon, Woo-Hyun (Department of Neurology, College of Oriental Medicine, Daeggu Haany University) ;
  • Baek, Kyung-Min (Department of Internal Medicine, College of Oriental Medicine, Daeggu Haany University) ;
  • Han, Chang-Hyun (TKM Information Research Division, Korea Institute of Oriental Medicine) ;
  • Jeon, Won-Kyung (Center for Herbal Medicine Improvement Research, Korea Institute of Oriental Medicine) ;
  • Gam, Cheol-Ou (Department of Internal Medicine, College of Oriental Medicine, Dong Eui University) ;
  • Lee, Young-Joon (Department of Preventive Medicine, College of Oriental Medicine, Daeggu Haany University)
  • 최성훈 (대구한의대학교 한의과대학 해부학교실) ;
  • 전우현 (대구한의대학교 한의과대학 신경과) ;
  • 백경민 (대구한의대학교 한의과대학 심계내과) ;
  • 한창현 (한국한의학연구원 문헌연구센터) ;
  • 전원경 (한국한의학연구원 신한방제제연구센터) ;
  • 감철우 (동의대학교 한의과대학 폐계내과) ;
  • 이영준 (대구한의대학교 한의과대학 예방의학교실)
  • Received : 2011.11.30
  • Accepted : 2011.12.22
  • Published : 2011.12.31

Abstract

Objectives : Vascular dementia is the second common cause of dementia after Alzheimer's disease. It assumed that the ratio of prescription drugs on vascular dementia are quite different from each hospital in Western medicine or Oriental medicine, respectively. The aim of this research is to collect and analyze the ratio of prescription drugs on vascular dementia in Western medicine or Oriental medicine in university hospitals. Methods : We collected and analyzed the data related to prescriptions on vascular dementia in the department of neurology in three university hospitals(A, B, C) and in the department of internal medicine in two Oriental medicine hospitals(Daegu Haany Oriental Hospital, Dong Eui Oriental Hospital). Results : In the department of neurology in A university hospital, donepezil(69.1%), memantine(14.0%), rivastigmine(12.3%), galantamine(4.5%) were prescribed in order. In B university hospital, galantamine(57.8%) donepezil(33.3%), rivastigmine(6.7%), donepezil with memantine(4.4%) were prescribed. In C university hospital, donepezil(62.0%), rivastigmine(25.0%), galantamine(7.0%) memantine(6.0%) were prescribed. The average frequencies of prescribed medication in the department of neurology in A, B, C university hospitals were donepezil(54.8%), galantamine(23.1%), rivastigmine(14.7%), memantine(7.4%). In Oriental medicine hospitals, various prescriptions have been used for vascular dementia. Among them, Ansincheongnoetang (安神淸腦湯) and Gamijihangeumja(加味地黃飮子) were often prescribed in Daegu Haany Oriental Hospital, and Bojungikgitang(補中益氣湯) in Dong Eui Oriental Hospital, too. Conclusions : Cholinesterase inhibitors such as donepezil, galantamine, rivastigmine and NMDA receptor inhibitor like memantine have been used as a drug of choice for vascular dementia in all surveyed university hospitals. In oriental hospitals, various prescriptions have been used for vascular dementia.

Keywords

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