The Korean Journal of Medicine

The Korean Association of Internal Medicine (대한내과학회)
권호 표지

Exercise-Induced Bronchoconstriction

운동 유발성 기도 수축

  • Park, Heung-Woo (Department of Internal Medicine, Seoul National University College of Medicine)
  • 박흥우 (서울대학교 의과대학 내과학교실)
  • Published : 2011.12.01
⟨ Previous Next ⟩

Abstract

Exercise-induced bronchoconstriction (EIB) is defined as transient, reversible bronchoconstriction that develops after strenuous exercise. If exercise is the only identified trigger for bronchoconstriction, it is called EIB. However, when it is associated with known asthma, then it is defined as EIB with asthma. The role of atopy in the pathogenesis of EIB has not been determined. In this issue of the journal, Kim et al. reported that atopy was a risk factor for EIB in young adult male patients, and sensitization to house dust mites was associated with EIB. This report shed a new light on the pathogenesis of EIB. However, additional large and confirmatory studies should be required to determine the possible association between atopy and EIB.

Keywords

References

  1. Randolph C. An update on exercise-induced bronchoconstriction with and without asthma. Curr Allergy Asthma Rep 2009;9: 433-438. https://doi.org/10.1007/s11882-009-0064-8
  2. Weiler JM, Bonini S, Coifman R, et al. American Academy of Allergy, Asthma & Immunology Work Group report: exerciseinduced asthma. J Allergy Clin Immunol 2007;119:1349-1358. https://doi.org/10.1016/j.jaci.2007.02.041
  3. Parsons JP, Mastronarde JG. Exercise-induced asthma. Curr Opin Pulm Med 2009;15:25-28. https://doi.org/10.1097/MCP.0b013e32831da8ab
  4. Anderson SD, Kippelen P. Airway injury as a mechanism for exercise-induced bronchoconstriction in elite athletes. J Allergy Clin Immunol 2008;122:225-235. https://doi.org/10.1016/j.jaci.2008.05.001
  5. Han JH, Kwon BH, Hyun KH, et al. Association of exercisenduced asthma with atopy in adult patients with asthma-like symptoms. Korean J Med 2011;81:723-728.
  6. Kim JH, Kim HB, Lee SY, Kim BS, Seo HJ, Hong SJ. Relationship between sensitization to individual aeroallergen, bronchial hyperresponsiveness and pulmonary function in atopic asthmatic children. Pediatr Allergy Respir Dis 2005;15:399-407.
  7. Chae HS, Kim YJ, Song DY, Kang IJ. The effect of atopy and airway eosinophilic inflammation on exercise-induced bronchospasm in asthmatics. Pediatr Allergy Respir Dis 2003;13:81-89.
  8. Rundell KW, Slee JB. Exercise and other indirect challenges to demonstrate asthma or exercise-induced bronchoconstriction in athletes. J Allergy Clin Immunol 2008;122:238-246. https://doi.org/10.1016/j.jaci.2008.06.014