Bulletin of the Korean Chemical Society

Korean Chemical Society (대한화학회)
권호 표지
DOI QR코드

DOI QR Code

Comparison of Enantioselective CEC Separation of OT-MIP Capillary Columns with Templates of Various Camphor Derivatives Made by the Pre-established General Preparation Protocol

  • Zaidi, Shabi Abbas (Department of Chemistry, Nano Fine Center, and Institute of Basic Research, Inha University) ;
  • Lee, Seung-Mi (Department of Chemistry, Nano Fine Center, and Institute of Basic Research, Inha University) ;
  • Lee, Ju-Young (Department of Chemistry, Nano Fine Center, and Institute of Basic Research, Inha University) ;
  • Cheong, Won-Jo (Department of Chemistry, Nano Fine Center, and Institute of Basic Research, Inha University)
  • Received : 2010.07.12
  • Accepted : 2010.08.05
  • Published : 2010.10.20
Download PDF
⟨ Previous Next ⟩

Abstract

Some open tubular (OT) molecule imprinted polymer (MIP) silica capillary columns with templates of camphor derivatives such as 10-camphorsulfonic acid (10-CSA), 10-camphorsulfonamide (10-CS) and camphor-p-tosyl hydrazone (CTH) have been successfully prepared by the prior generalized preparation protocol. The three MIP thin layers of different templates showed quite different morphologies. The chiral selectivity of each MIP column for the template enantiomers was optimized by changing eluent composition and pH. The optimization conditions were found to be different for the three MIPs. This work suggests prospective successful extension of the generalized preparation protocol for OT-MIP silica capillary columns toward templates of a variety of chemical groups.

Keywords

References

  1. Vlatakis, G.; Andersson, L. I.; Muller, R.; Mosbach, K. Nature 1993, 361, 645-647. https://doi.org/10.1038/361645a0
  2. Klein, J. U.; Whitecombe, M. J.; Mulhollard, F.; Vulfson, E. N. Angew. Chem. Int. Ed. Engl. 1999, 38, 2057-2060. https://doi.org/10.1002/(SICI)1521-3773(19990712)38:13/14<2057::AID-ANIE2057>3.0.CO;2-G
  3. Zaidi, S. A.; Cheong, W. J. J. Chromatogr. A 2009, 1216, 2947-2952. https://doi.org/10.1016/j.chroma.2008.08.015
  4. Wulff, G. Angew. Chem. Int. Ed. Engl. 1995, 34, 1812-1832. https://doi.org/10.1002/anie.199518121
  5. Sellergren, B.; Shea, K. J. J. Chromatogr. A 1993, 635, 31-49. https://doi.org/10.1016/0021-9673(93)83112-6
  6. Schweitz, L.; Andersson, L. I.; Nilsson, S. J. Chromatogr. A 1998, 817, 5-13. https://doi.org/10.1016/S0021-9673(98)00417-8
  7. Vallano, P. T.; Remcho, V. T. J. Chromatogr. A 2000, 887, 125-135. https://doi.org/10.1016/S0021-9673(99)01199-1
  8. Zaidi, S. A.; Han, K. M.; Kim, S. S.; Hwang, D. G.; Cheong, W. J. J. Sep. Sci. 2009, 32, 996-1001. https://doi.org/10.1002/jssc.200800631
  9. Nilsson. S.; Schweitz, L.; Petersson, M. Electrophoresis 1997, 18, 884-890. https://doi.org/10.1002/elps.1150180606
  10. Zaidi, S. A.; Cheong, W. J. Electrophoresis 2009, 30, 1603-1607. https://doi.org/10.1002/elps.200800541
  11. Zaidi, S. A.; Han, K. M.; Hwang, D. G.; Cheong, W. J. Electrophoresis 2010, 31, 1-10. https://doi.org/10.1002/elps.200990124
  12. The Merck index, An Encyclopedia of Chemicals, Drugs and Biologicals, 12th ed.; 1996; Merck Research Laboratories, Division of Merck & Co., Inc.: NJ.
  13. Park, J. H.; Ryu, J. K.; Park, J. K.; Mcneff, C. V.; Carr, P. W. Chromatographia 2001, 58, 405-408.
  14. Kagan, M.; Chlenov, M.; Greenfield, A.; Ho, D. M. J. Chromatogr. A 2006, 1120, 82-88. https://doi.org/10.1016/j.chroma.2005.12.109
  15. Gonzalez, G. P.; Hernando, P. F.; Algeria, J. S. D. Anal. Chim. Acta 2006, 557, 179-183. https://doi.org/10.1016/j.aca.2005.10.034
  16. Xu, Y. L.; Liu, Z. S.; Wang, H. F.; Yan, C.; Gao, R. Y. Electrophoresis 2005, 26, 804-811. https://doi.org/10.1002/elps.200410171

Cited by

  1. Open Tubular Molecular Imprinted Polymer Fabricated in Silica Capillary for the Chiral Recognition of Neutral Enantiomers in Capillary Electrochromatography vol.33, pp.5, 2012, https://doi.org/10.5012/bkcs.2012.33.5.1664
  2. Molecular imprinting science and technology: a survey of the literature for the years 2004-2011 vol.27, pp.6, 2014, https://doi.org/10.1002/jmr.2347
  3. Graphene oxide coated capillary for the analysis of endocrine-disrupting chemicals by open-tubular capillary electrochromatography with amperometric detection vol.37, pp.13, 2014, https://doi.org/10.1002/jssc.201301126
  4. Open tubular capillary columns with basic templates made by the generalized preparation protocol in capillary electrochromatography chiral separation and template structural effects on chiral separati vol.1218, pp.9, 2010, https://doi.org/10.1016/j.chroma.2010.12.117
  5. Recent advances in capillary electrochromatography using molecularly imprinted polymers vol.35, pp.19, 2010, https://doi.org/10.1002/elps.201400253
  6. Separation of histidine enantiomers by capillary electrochromatography with molecularly imprinted monolithic columns vol.3, pp.6, 2020, https://doi.org/10.1002/sscp.201900101
  7. Functional materials in chiral capillary electrophoresis vol.445, pp.None, 2021, https://doi.org/10.1016/j.ccr.2021.214108