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소목(蘇木)과 황련(黃連) 추출물(抽出物)의 Bacillus cereus와 Vibrio parahaemolyticus 에 대한 항세균활성(抗細菌活性)

Antibacterial Activity of Caesalpinia sappan and Coptis chinensis Extracts against Bacillus cereus and Vibrio parahaemolyticus

  • 이건희 (중부대학교 한방제약과학과) ;
  • 도은수 (중부대학교 한방제약과학과) ;
  • 장준복 (중부대학교 한방제약과학과) ;
  • 길기정 (중부대학교 한방제약과학과)
  • Lee, Gun-Hee (Dept. of Herbal Pharmaceutical Science, Joongbu University) ;
  • Doh, Eun-Soo (Dept. of Herbal Pharmaceutical Science, Joongbu University) ;
  • Chang, Jun-Pok (Dept. of Herbal Pharmaceutical Science, Joongbu University) ;
  • Kil, Gi-Jung (Dept. of Herbal Pharmaceutical Science, Joongbu University)
  • 투고 : 2010.08.13
  • 심사 : 2010.09.13
  • 발행 : 2010.09.30

초록

Objectives : This experimental study was performed to investigate the antibacterial effect of Caesalpinia sappan and Coptis chinensis extract against B. cereus and V. parahaemolyticus. Methods : Methanol extracts of C. sappan and C. chinensis was tested against B. cereus and V. parahaemolyticus by paper disc method. Results : The growth of B. cereus and V. parahaemolyticus was inhibited by C. sappan and C. chinensis extract among 6 kinds of medicinal plant extracts. The extract of C. sappan and C. chinensis extract inhibited the growth of V. parahaemolyticus and B. cereus, respectively. The growth of B. cereus and V. parahaemolyticus had a tendency to increase depend on the concentration of the extract. EtOEt and EtOAc fractions and EtOEt and BuOH fractions of the C. sappan extract had a high antibacterial activity against B. cereus and V. parahaemolyticus, respectively. And, BuOH and $H_2O$ fractions of the C. chinensis extract showed antibacterial activity against B. cereus highly. Conclusions : C. sappan and C. chinensis extract efficiently inhibited the growth of B. cereus and V. parahaemolyticus.

키워드

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