생약학회지 (Korean Journal of Pharmacognosy)

  • 제41권1호
  • /
  • Pages.58-61
  • /
  • 2010
  • /
  • 0253-3073(pISSN)
  • /
  • 2288-9299(eISSN)
한국생약학회 (The Korean Society of Pharmacognosy)
권호 표지

고체발효 숙지황의 지표성분 함량분석

Quantitative Analysis of Marker Substance in Fermented Rehmanniae Radix Preparata

  • 박화용 (한국한의학연구원 신한방제제연구센터) ;
  • 엄영란 (한국한의학연구원 신한방제제연구센터) ;
  • 마진열 (한국한의학연구원 신한방제제연구센터)
  • Park, Hwa-Yong (Center for Herbal Medicine Improvement Research, Korea Institute of Oriental Medicine) ;
  • Um, Young-Ran (Center for Herbal Medicine Improvement Research, Korea Institute of Oriental Medicine) ;
  • Ma, Jin-Yeul (Center for Herbal Medicine Improvement Research, Korea Institute of Oriental Medicine)
  • 투고 : 2010.01.23
  • 발행 : 2010.03.31
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초록

Medicinal plant Rehmanniae Radix has long been used as traditional herbal medicine in Korea. In this study, we investigated quantitative changes of marker substance 5-hydroxymethyl-2-furaldehyde (5-HMF) in Rehmanniae Radix Preparata fermented with Ganoderma lucidum, Paecilomyces japonica, honey, and Nuruk, using HPLC according to the Korean Pharmacopoeia. As a result, 5-HMF was decreased in SDT and SYT, and increased in SST and SNT, comparing with control group. Quantitative increasing of 5-HMF is not exactly in direct proportion with fermentation, and it is need further studies to elucidate mechanism of quantitative changes by converted and newly produced substances with fermentation.

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