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Quantitative Analysis of Marker Substance in Fermented Rehmanniae Radix Preparata  

Park, Hwa-Yong (Center for Herbal Medicine Improvement Research, Korea Institute of Oriental Medicine)
Um, Young-Ran (Center for Herbal Medicine Improvement Research, Korea Institute of Oriental Medicine)
Ma, Jin-Yeul (Center for Herbal Medicine Improvement Research, Korea Institute of Oriental Medicine)
Publication Information
Korean Journal of Pharmacognosy / v.41, no.1, 2010 , pp. 58-61 More about this Journal
Abstract
Medicinal plant Rehmanniae Radix has long been used as traditional herbal medicine in Korea. In this study, we investigated quantitative changes of marker substance 5-hydroxymethyl-2-furaldehyde (5-HMF) in Rehmanniae Radix Preparata fermented with Ganoderma lucidum, Paecilomyces japonica, honey, and Nuruk, using HPLC according to the Korean Pharmacopoeia. As a result, 5-HMF was decreased in SDT and SYT, and increased in SST and SNT, comparing with control group. Quantitative increasing of 5-HMF is not exactly in direct proportion with fermentation, and it is need further studies to elucidate mechanism of quantitative changes by converted and newly produced substances with fermentation.
Keywords
Rehmanniae Radix Preparata; fermentation; 5-HMF;
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Times Cited By SCOPUS : 2
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