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만성기침 환자에서 Chlamydia pneumoniae 감염률

Infection Rate of Chlamydia pneumoniae in Patients with Chronic Cough

  • 천승연 (한림대학교 의과대학 내과학교실) ;
  • 박권오 (한림대학교 의과대학 내과학교실) ;
  • 박용범 (한림대학교 의과대학 내과학교실) ;
  • 최정희 (한림대학교 의과대학 내과학교실) ;
  • 이재영 (한림대학교 의과대학 내과학교실) ;
  • 모은경 (한림대학교 의과대학 내과학교실) ;
  • 박성훈 (한림대학교 의과대학 내과학교실) ;
  • 김철홍 (한림대학교 의과대학 내과학교실) ;
  • 이창률 (한림대학교 의과대학 내과학교실) ;
  • 황용일 (한림대학교 의과대학 내과학교실) ;
  • 장승훈 (한림대학교 의과대학 내과학교실) ;
  • 신태림 (한림대학교 의과대학 내과학교실) ;
  • 박상면 (한림대학교 의과대학 내과학교실) ;
  • 김동규 (한림대학교 의과대학 내과학교실) ;
  • 이명구 (한림대학교 의과대학 내과학교실) ;
  • 현인규 (한림대학교 의과대학 내과학교실) ;
  • 정기석 (한림대학교 의과대학 내과학교실)
  • Chun, Seung-Yeon (Department of Internal Medicine, Hallym University College of Medicine) ;
  • Park, Kwon-Oh (Department of Internal Medicine, Hallym University College of Medicine) ;
  • Park, Yong-Bum (Department of Internal Medicine, Hallym University College of Medicine) ;
  • Choi, Jeong-Hee (Department of Internal Medicine, Hallym University College of Medicine) ;
  • Lee, Jae-Young (Department of Internal Medicine, Hallym University College of Medicine) ;
  • Mo, Eun-Kyung (Department of Internal Medicine, Hallym University College of Medicine) ;
  • Park, Sung-Hoon (Department of Internal Medicine, Hallym University College of Medicine) ;
  • Kim, Cheol-Hong (Department of Internal Medicine, Hallym University College of Medicine) ;
  • Lee, Chang-Youl (Department of Internal Medicine, Hallym University College of Medicine) ;
  • Hwang, Yong-Il (Department of Internal Medicine, Hallym University College of Medicine) ;
  • Jang, Seung-Hun (Department of Internal Medicine, Hallym University College of Medicine) ;
  • Shin, Tae-Rim (Department of Internal Medicine, Hallym University College of Medicine) ;
  • Park, Sang-Myeon (Department of Internal Medicine, Hallym University College of Medicine) ;
  • Kim, Dong-Gyu (Department of Internal Medicine, Hallym University College of Medicine) ;
  • Lee, Myung-Goo (Department of Internal Medicine, Hallym University College of Medicine) ;
  • Hyun, In-Gyu (Department of Internal Medicine, Hallym University College of Medicine) ;
  • Jung, Ki-Suck (Department of Internal Medicine, Hallym University College of Medicine)
  • 투고 : 2010.09.24
  • 심사 : 2010.10.06
  • 발행 : 2010.12.30

초록

Background: Persistent cough has recently been found to be associated with Chlamydia pneumoniae infection. We aimed to investigate the infection rate of C. pneumonia in adult patients with chronic cough. Methods: We recruited 68 patients with persistent cough lasting in excess of 3 weeks, who visited Kangdong Sacred Heart Hospital from January 2005 to August 2005. On the first visit, chest and paranasal sinuses radiography, skin prick test of common allergens, and induced sputum samples for C. pneumoniae were performed in all of patients. Further evaluation for diagnosis included a methacholine provocation test and eosinophil counts in induced sputum. Results: The most common cause of chronic cough was upper airway cough syndrome (UACS) (26.5%), followed by eosinophilic bronchitis (20.6%) and cough variant asthma (16.2%). Idiopathic chronic cough was the cause in 33.8% of patients. The mean duration of cough was 11.7 months. C. pneumoniae was isolated by polymerase chain reaction (PCR) from one patient who had upper respiratory air way syndrome. Conclusion: Chlamydia pneumoniae appears to have a minor role as a cause of chronic cough in patients.

키워드

참고문헌

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