Pediatric Infection and Vaccine

  • 제17권2호
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  • Pages.130-136
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  • 2010
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  • 2384-1079(pISSN)
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  • 2384-1087(eISSN)
대한소아감염학회 (The Korean Society of Pediatric Infectious Diseases)
권호 표지

부산지역 급성 호흡기 증상으로 외래 방문한 환자의 바이러스 원인과 역학: 2007-2008년

Viral Etiology and Epidemiology of Outpatients with Acute Respiratory Illnesses in Busan: 2007-2008

  • 정진우 (부산성모병원 소아청소년과) ;
  • 황윤하 (부산성모병원 소아청소년과) ;
  • 조경순 (부산보건환경연구원) ;
  • 정명주 (부산보건환경연구원) ;
  • 민상기 (부산보건환경연구원) ;
  • 김성준 (부산보건환경연구원) ;
  • 정우식 (부산성모병원 소아청소년과)
  • Jeong, Jin Woo (Department of Pediatrics, Busan St. Mary's Medical Center) ;
  • Hwang, Youn Ha (Department of Pediatrics, Busan St. Mary's Medical Center) ;
  • Cho, Kyung Soon (Busan Metropolitan City Institute of Health & Environment) ;
  • Jung, Myung Ju (Busan Metropolitan City Institute of Health & Environment) ;
  • Min, Sang Kee (Busan Metropolitan City Institute of Health & Environment) ;
  • Kim, Seong Joon (Busan Metropolitan City Institute of Health & Environment) ;
  • Chung, Woo Sik (Department of Pediatrics, Busan St. Mary's Medical Center)
  • 투고 : 2010.09.15
  • 심사 : 2010.10.19
  • 발행 : 2010.12.25
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초록

목적 : 부산에서 급성호흡기 증상으로 외래 방문한 환자를 대상으로 원인 바이러스 및 역학을 연구하고자 하였다. 방법 : 2007년 1월부터 2008년 12월까지 3개 병원 소아청소년과 외래에 급성 호흡기 증상을 주소로 내원한 990명을 대상으로, 비강 세척법으로 검체를 채취하여 역전사중합효소연쇄반응을 시행하였다. 결과 : 총 검체 990건 중 351건(35.5%)이 검출되었으며, 남녀 비는 1.6대 1이었고, 5세 이하가 93.7%였다. hRV가 가장 흔한 원인으로 연중 202건(57.5%), 그 다음으로는 RSV로 10월부터 3월까지 57건(16.2%), ADV는 연중 37건(10.5%), INF는 12월부터 4월까지 21건(6%), hBoV는 1월부터 8월까지 15건(4.3%), PIV는 4월부터 7월까지 9건(2.6%), hCoV는 1월부터 7월까지 7건(2%), EV는 6월부터 9월에 3건(0.9%) 검출되었다. 결론 : 본 연구는 부산의 소아급성호흡기 질환을 예방하고 치료하는데 도움이 되고자 하며, 앞으로도 원인 바이러스에 대한 지속적인 연구가 필요하다.

Purpose : The purpose of this study is to identify the viral etiology of acute respiratory illnesses and to determine epidemiology in outpatients in Busan, Korea. Methods : We collected nasal wash samples from 990 patients who visited the hospital for acute respiratory illnesses between January 2007 and December 2008. Extracted DNA or RNA from specimens was used for viral detection by an RT-PCR method. Results : Of a total of 990 samples, viruses were detected in 351 cases (35.5%). The ratio of male to female was 1.6:1 and 93.7% were less than 5 years old. Rhinovirus was detected year-round in 202 cases (57.5%), respiratory syncytial virus from October to March in 57 cases (16.2%), adenovirus year-round in 37 cases (10.5%), influenza virus from December to April in 21 cases (6%), bocavirus from January to August in 15 cases (4.3%), parainfluenza virus from April to July in 9 cases (2.6%), coronavirus from January to July in 7 cases (2%), and enterovirus from June to September in 3 cases (0.9%). Conclusion : We identified the etiology and epidemiology of viruses that caused the acute respiratory diseases that were prevalent in Busan, 2007-2008. Further surveillance will be necessary.

키워드

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