한국의학물리학회지:의학물리 (Progress in Medical Physics)

  • 제21권4호
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  • Pages.354-359
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  • 2010
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  • 2508-4445(pISSN)
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  • 2508-4453(eISSN)
한국의학물리학회 (Korean Society of Medical Physics)
권호 표지

뇌하수체 종양의 방사선 수술 시 영상 융합 프로토콜이 실제 PTV와 OAR 선량에 미치는 영향

The Dosimetric Effect on Real PTV and OARs at Various Image Fusion Protocol for Pituitary Adenomas

  • 이경남 (가톨릭대학교 의과대학 의공학교실) ;
  • 이동준 (인제대학교 의과대학 신경외과학교실) ;
  • 서태석 (가톨릭대학교 의과대학 의공학교실)
  • Lee, Kyung-Nam (Department of Biomedical Engineering, The Catholic University of Korea College of Medicine) ;
  • Lee, Dong-Joon (Department of Neurosurgery, College of Medicine, Inje University) ;
  • Suh, Tae-Suk (Department of Biomedical Engineering, The Catholic University of Korea College of Medicine)
  • 투고 : 2010.12.06
  • 심사 : 2010.12.15
  • 발행 : 2010.12.31
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초록

뇌하수체 종양의 치료 계획 시 다양한 영상 융합 프로토콜이 실제 PTV (planning target volume) coverage 및 OAR (organ at risk) 보호에 미치는 선량학적 영향을 확인하고자 하였다. 선량 체적 히스토그램(DVH, dose volume histogram)을 이용하여 각 프로토콜 별 실제 PTV의 coverage 및 그 변화 그리고 시각경로(optic pathway) 및 뇌간(brainstem)의 최대 흡수 선량과 임계 선량을 초과한 체적을 획득하였고 축상면(axial plane)과 관상면(coronal) 영상을 함께 사용하여 S-I (superior-inferior) 방향의 불확정도를 보정한 영상 융합 프로토콜이 축상면 만을 이용한 경우보다 시각경로 및 뇌간의 최대 흡수 선량과 임계 선량을 초과한 체적 모두 감소된 수치를 보임을 확인 하였다. 본 case에 한해 축상면 그리고 관상면 영상을 함께 사용하는 것이 OARs 보호에 가중치를 둔 방사선 수술 치료 계획 수립에 도움을 줄 수 있다.

The purpose of this study is to verify the dosimetric effect on real PTV (planning target volume) coverage and safety of OARs (organs at risk) at various image fusion protocol-based radiosurgery plan for pituitary adenomas. Real PTV coverage and its variation was acquired and maximum dose and the volume absorbing above threshold dose were also measured for verifying the safety of optic pathway and brainstem. The protocol that can reduce superior-inferior uncertainty by using both axial and coronal MR (magnetic resonance) image sets shows relatively lower values than that of case using only axial image sets. As a result, the image fusion protocol with both axial and coronal image sets can be beneficial to generate OAR-weighted radiosurgery plan.

키워드

참고문헌

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