Histopathology of unidentified viral disease of cultured carp Cyprinus carpio

양식 잉어, Cyprinus carpio에서 발생하는 미동정 바이러스성 질병의 병리조직학적 특징

  • Seo, Jang-Woo (Aquaculture Industry Division, Ministry for Food, Agriculture, Forestry and Fisheries) ;
  • Kim, Wi-Sik (Department of Aqualife Medicine, College of Fisheries and Ocean Science, Chonnam National University) ;
  • Kim, Jong-Oh (Department of Aqualife Medicine, College of Fisheries and Ocean Science, Chonnam National University) ;
  • Jung, Sung-Ju (Department of Aqualife Medicine, College of Fisheries and Ocean Science, Chonnam National University) ;
  • Kim, Seok-Ryel (Pathology Division, National Fisheries Research and Development Institute) ;
  • Park, Myoung-Ae (Pathology Division, National Fisheries Research and Development Institute) ;
  • Oh, Myung-Joo (Department of Aqualife Medicine, College of Fisheries and Ocean Science, Chonnam National University)
  • 서장우 (농림수산식품부 양식산업과) ;
  • 김위식 (전남대학교 수산생명의학과) ;
  • 김종오 (전남대학교 수산생명의학과) ;
  • 정성주 (전남대학교 수산생명의학과) ;
  • 김석렬 (국립수산과학원 병리연구과) ;
  • 박명애 (국립수산과학원 병리연구과) ;
  • 오명주 (전남대학교 수산생명의학과)
  • Received : 2009.12.18
  • Accepted : 2010.04.02
  • Published : 2010.04.30

Abstract

Unidentified viral disease with high mortalities has been recorded consistently since 1998 in cultured carp Cyprinus carpio in Korea. In the present study, we investigated the histopathological characteristics of the diseased carp to evaluate the relatedness to koi herpesvirus disease (KHVD). Histopathogical examination revealed severe necrotic changes and vacuous cells in the kidney, spleen, liver, pancreas, heart and intestine, but eosinophilic intranuclear inclusion, a typical characteristic of KHV infection was not detected. These results suggest that KHVD may be not a cause for the high mortality occurring among cultured carp in Korea and possibly other unknown viral disease could are related.

국내 양식잉어는 1998년부터 잉어바이러스성 질병으로 인해 대량 폐사되었다. 본 연구에서는 잉어바이러스성 질병과 KHV병과의 연관성을 조사하기 위하여 잉어바이러스성 질병으로 대량 폐사된 잉어를 대상으로 병리조직학적 검사를 실시하여 병리적 병변을 비교하였다. 병리조직학적 검사 결과, 괴사병소와 공포성 세포를 특징으로 하는 특이 병변이 신장, 비장, 간, 췌장, 심장 및 소화관에서 관찰되어 전신성 병변을 보였으나, KHV병의 특이적 병변인 호산성 핵내 봉입체를 가진 세포들은 관찰되지 않았다. 이상의 결과로 국내에서 발생하는 잉어바이러스성 질병은 KHV병과는 다른 새로운 바이러스성 질병으로 사료되었다.

Keywords

References

  1. Hedrick, R.P., Gilad, O., Yun, S. and Spangenberg J.V.: A herpesvirus associated with mass mortality of juvenile and adult koi, a strain of common carp. J. Aquat. Anim. Health, 12:44-57, 2000. https://doi.org/10.1577/1548-8667(2000)012<0044:AHAWMM>2.0.CO;2
  2. Miyazaki, T., Kuzuya, Y., Yasumoto, S., Yasuda, M. and Kobayashi, T.: Histopathological and ultrastructural features of koi herpesvirus (KHV)-infected carp Cyprinus carpio, and the morphology and morphogenesis of KHV. Dis. Aquat. Org., 80:1-11, 2008. https://doi.org/10.3354/dao01929
  3. Oh, M.J., Jung, S.J., Choi, T.J., Kim, H.R., Rajendran, K.V., Kim, Y.J. Pack, M.A. and Chun, S.K.: A viral disease occurring in cultured carp Cyprinus carpio in Korea. Fish Pathol., 36:147-151, 2001. https://doi.org/10.3147/jsfp.36.147
  4. OIE: Manual of diagnostic tests for aquatic animals. Koi herpesvirus disease, 2009.
  5. Sano, M., Ito, T., Kurita, J., Yanai, T., Watanabe, N., Miwa, S. and Iida, T.: First detection of koi herpesvirus in cultured common carp Cyprinus carpio in Japan. Fish Pathol., 39:165-167, 2004. https://doi.org/10.3147/jsfp.39.165