유한요소해석을 이용한 연골세포와 세포겉기질의 결합력 분석

Analysis of the Bonding Strength between PCM and Chondrocyte Using FEM

  • 최재봉 (한성대학교 기계시스템공학과) ;
  • 한정수 (한성대학교 기계시스템공학과)
  • Choi, Jae-Bong (Department of Mechanical Systems Engineering, Hansung Univ.) ;
  • Han, Jung-Soo (Department of Mechanical Systems Engineering, Hansung Univ.)
  • 발행 : 2009.07.01

초록

키워드

참고문헌

  1. Buschmann, M. D., Hunziker, E. B., Kim, Y. and Grodzinsky, A. J., "Altered aggrecan synthesis correlates with cell and nuleus structur statically compressed cartilage," J. Cell Sci., Vol. 109, No. 2,pp. 499-508, 1996
  2. Alexopoulos, L. G., Haider, M. A., Vail, T. P. and Guilak, F., "Alteration Alterations in the Mechanical Properties of the Human Chondrocyte Pericellular Matrix With Osteoarthritis," J. Biomech. Eng., Vol. 125, No. 3, pp.323-333, 2003 https://doi.org/10.1115/1.1579047
  3. Mow, V. C., Kuei, S. C., Lai, W. M. and Armstrong,C. G., "Biphasic creep and stress relaxation of articular cartilage in compression : theory and experiments," J. Biomech. Eng., Vol. 102, No. 1, pp.73-84, 1980 https://doi.org/10.1115/1.3138202
  4. Guilak, F., Tedorw, J. R. and Burgkart, R.,"Viscoelastic properties of the cell nucleus," Bioch. Biophy. Res. Comm., Vol. 269, No. 3, pp. 781-786, 2000 https://doi.org/10.1006/bbrc.2000.2360
  5. Youn, I., Choi, J. B., Cao, L., Setton, L. A. andGuilak, F., "Zonal variation in the three-dimensionalmorphology of the chondron measured in situ usingconfocal microscopy," Osteoarthritis and Cartilage,Vol. 14, No. 9, pp. 889-897, 2006 https://doi.org/10.1016/j.joca.2006.02.017
  6. Leipzig, N. D. and Athanasiou, K. A., "Unconfinedcreep compression of chondrocyte," J. of Biomechanics, Vol. 38, No. 1, pp. 77-85, 2005 https://doi.org/10.1016/j.jbiomech.2004.03.013
  7. Trickey, W. R., Vail, T. P. and Guilak, F., "The role of the cytoskeleton in the viscoelastic properties of human articular chondrocytes," J. Ortho. Res., Vol. 22, No. 1, pp. 131-139, 2004 https://doi.org/10.1016/S0736-0266(03)0150-5
  8. Knight, M. M., Lee, D. A. and Bader, D. L., "Theinfluence of elaborated pericellular matrix on thedeformation of isolated articular chondrocyte culturedin agarose," Biochi. Biophy. Acta, Vol. 1405, No. 1-3,pp. 67-77, 1998 https://doi.org/10.1016/S0167-4889(98)00102-5
  9. Ting-Beall, H. P., "The effects of osmotic stress onthe viscoelastic and physical properties of articular chondrocytes," Biophy. J., Vol. 82, No. 2, pp. 720-727, 2002 https://doi.org/10.1016/S0006-3495(02)75434-9
  10. Guilak, F. and Mow, V. C., "The Mechanical environment of the chondrocyte: a biphasic finite element model of cell-matrix interaction in articular cartilage," J. of Biomechanics, Vol. 33, No. 12, pp.1663-1673, 2000 https://doi.org/10.1016/S0021-9290(00)00105-6
  11. Wu, J. Z., Herzog, W. and Epstein, M., "Modelling of location- and time-dependent deformation of chondrocyte during cartilage loading," J. of Biomechanics, Vol. 32, No. 6, pp. 563-572, 1999 https://doi.org/10.1016/S0021-9290(99)00034-2
  12. Jones, W. R., Ting-Beall, H. P., Lee, G. M., Kelley, S.S., Hochmuth, R. M. and Guilak, F., "Alteration in the Young's modulus and volumetric properties of chondrocytes isolated from normal and osteoarthritic human cartilage," J. of Biomechanics, Vol. 32, No. 2,pp. 119-127, 1999 https://doi.org/10.1016/S0021-9290(98)00166-3
  13. Jin, H. and Lewis, J. L., "Determination of Poisson's ratio of articular cartilage by indentation using different-sized indenter," Transaction of the ASME,Vol. 126, No. 2, pp. 138-145, 2004 https://doi.org/10.1115/1.1688772
  14. Clark, A. L., Barclay, L. D., Matyas, J. R. and Herzog, W., "In situ chondrocyte deformation with physiological compression of the feline patellofemoral joint," J. of Biomechanics, Vol. 36,No. 4, pp. 553-568, 2003 https://doi.org/10.1016/S0021-9290(02)00424-4
  15. Hing, W. A., Sherwin, A. F., Ross, J. M. and Poole, C.A., "The influence of the pericellular microenvironment on the chondrocyte response to osmotic challenge," Osteoarthritis and Cartilage, Vol.10, No. 4, pp. 297-307, 2002 https://doi.org/10.1053/joca.2002.0517
  16. Choi, J. B., Youn, I., Cao, L., Leddy, H. A., Gilchrist,C. L., Setton, L. A. and Guilak, F., "Zonal changes in the three-dimensional morphology of the chondronunder compression: The relationship among cellular,pericellular, and extracellular deformation in articular cartilage," J. of Biomechanics, Vol. 40, No. 12, pp.2596-2503, 2007 https://doi.org/10.1016/j.jbiomech.2007.01.009
  17. Alexopoulos, L. G., Williams, G. M., Upton, M. L.,Setton, L. A. and Guilak, F., "Osteoarthritic changes in the biphasic mechanical properties of the chondrocytet pericellular marix in articular cartilage,"J. of Biomechanics, Vol. 38, No. 3, pp. 509-517, 2005 https://doi.org/10.1016/j.jbiomech.2004.04.012
  18. Durrant, L. A., Archer, C. W., Benjamin, M. andRalphs, J. R., "Organization of the chondrocyte cytoskeleton and its response to changing mechanical conditions in organ culture," J. Anat., Vol. 194, Part 3, pp. 343-353, 1999 https://doi.org/10.1046/j.1469-7580.1999.19430343.x