Journal of Pharmaceutical Investigation

The Korean Society of Pharmaceutical Sciences and Technology (한국약제학회)
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Comparative evaluation of water vapor transmission rate of PVA/Dextran blended hydrogel using European Pharmacopiea and Japanese Industrial Standards method

유럽 약전과 일본 산업기준 규격 방식에 의한 폴리비닐 알코올 및 덱스트란 함유 하이드로겔의 투습률 비교평가

  • Published : 2009.04.27
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Abstract

To compare the water vapor transmission rate (WVTR) of PVA/Dextran blended hydrogel obtained by European Pharmacopiea (EP) and Japanese Industrial Standards 1099 (JIS) method, the hydrogels with various PVA/Dextran rates were prepared and their WVTR values were then checked. As dextran in the hydrogel was increased, the WVTR of hydrogel was increased. The WVTR of hydrogels were 660-1500 and $730-1900\;g/m^2$-day in EP and JIS method, respectively. There were no significant differences between the WVTRs of the hydrogels obtained by EP and those obtained by JIS method. Thus, JIS method was recommended as a WVTR method of hydrogel due to relatively simpler and shorter time.

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