Browse > Article
http://dx.doi.org/10.4333/KPS.2009.39.2.093

Comparative evaluation of water vapor transmission rate of PVA/Dextran blended hydrogel using European Pharmacopiea and Japanese Industrial Standards method  

Choi, Han-Gon (College of Pharmacy, Yeungnam University)
Hwang, Ma-Ro (College of Pharmacy, Yeungnam University)
Oh, Dong-Hoon (College of Pharmacy, Yeungnam University)
Li, Dong-Xun (College of Pharmacy, Yeungnam University)
Kim, Jong-Oh (College of Pharmacy, Yeungnam University)
Lee, Jeong-Hoon (College of Pharmacy, Yeungnam University)
Woo, Jong-Soo (College of Pharmacy, Yeungnam University)
Yong, Chul-Soon (College of Pharmacy, Yeungnam University)
Publication Information
Journal of Pharmaceutical Investigation / v.39, no.2, 2009 , pp. 93-95 More about this Journal
Abstract
To compare the water vapor transmission rate (WVTR) of PVA/Dextran blended hydrogel obtained by European Pharmacopiea (EP) and Japanese Industrial Standards 1099 (JIS) method, the hydrogels with various PVA/Dextran rates were prepared and their WVTR values were then checked. As dextran in the hydrogel was increased, the WVTR of hydrogel was increased. The WVTR of hydrogels were 660-1500 and $730-1900\;g/m^2$-day in EP and JIS method, respectively. There were no significant differences between the WVTRs of the hydrogels obtained by EP and those obtained by JIS method. Thus, JIS method was recommended as a WVTR method of hydrogel due to relatively simpler and shorter time.
Keywords
Water vapor transmission; wound dressing; hydrogel; European Pharmacopiea; Japanese Industrial Standards;
Citations & Related Records
연도 인용수 순위
  • Reference
1 C.D. Hinman and H. Maibach, Effect of air exposure and occlusion on experimental human skin wounds, Nature, 200, 377-378 (1963).   DOI   ScienceOn
2 A.S. Hoffman, Hydrogels for biomedical applications, Adv. Drug Deliver. Rev., 43, 3-12 (2002).   DOI   ScienceOn
3 T.S. Stashak, E. Farstvedt and A. Othic, Update on wound dressings: Indications and best use, Clinical Techniques in Equine Practice, 3(2), 148-163 (2004).   DOI   ScienceOn
4 M. Kokabi, M. Sirousazar and Z.M. Hassan, PVA-clay nanocomposite hydrogels for wound dressing, Eur. Polym. J., 43, 773-781 (2007).   DOI   ScienceOn
5 N.F.S. Watson and W. Dabell, Wound dressings, The Foundation Years, 2(1), 38-41 (2006).   DOI   ScienceOn
6 J.H. Yeo, K.G. Lee, H.C. Kim, Y.L. Oh, A.J. Kim and S.Y. Kim, The effects of PVA/chitosan/fibroin (PCF)-blended spongy sheets on wound healing in rats, Biol. Pharm. Bull., 23(10), 1220-1223 (2000).   DOI   ScienceOn
7 W.C. Lin, D.G. Yu and M.C. Yang, Blood compatibility of novel PGA (poly glutamic acid) / poly vinyl alcohol hydrogels, Colloids Surf. B. Biointerfaces, 47(1), 43-49 (2006).   DOI   ScienceOn
8 Z. Ajji, G. Mirjalili, A. Alkhatab and H. Dada, Use of electron beam for the production of hydrogel dressings, Radiat. Phys. Chem., 77(2), 200-202 (2008).   DOI   ScienceOn
9 D. Queen, J.D.S. Gaylor, J.H. Evans, J.M. Courtney and W.H. Reid, The preclinical evaluation of the water vapour transmission rate through burn wound dressings, Biomaterials, 8, 367–371 (1987).
10 T.D.Turner, Hospital usage of absorbent dressings, Pharmaceutical J., 222, 421-424 (1979).
11 M.T. Razzak, D. Darwis and Z. Sukirno, Irridation of polyvinyl alcohol and polyvinyl pyrrolidone blended hydrogel for wound dressing, Radiat. Phys. Chem., 62, 107-113 (2001).   DOI   ScienceOn
12 M.H. Huang and M.C. Yang, Evaluation of glucan/poly (vinyl alcohol) blend wound dressing using rat models, Int. J. Pharm., 346, 38-46 (2008).   DOI   ScienceOn
13 M.G Cascone, S. Maltinti and N. Barbani, Effect of chitosan and dextran on the properties of poly (vinyl alcohol) hydrogels, J. Mater. Sci.-Mater., 10, 431-435 (1999).   DOI   ScienceOn
14 G.D. Winter, Formation of the scab and the rate of epithelization of superficial wounds in the skin of the young domestic pig, Nature, 193, 293-294 (1962).   DOI   ScienceOn
15 R.J. Morin and N.L. Tomaselli, Interactive dressings and topical agents, Clin. Plast. Surg., 34, 643-658 (2007).   DOI   ScienceOn