YAKHAK HOEJI (약학회지)

The Pharmaceutical Society of Korea (대한약학회)
권호 표지

Synthesis of Bis(pyronyl)acrylic Acid Ester Derivatives

Bis(pyronyl)acrylic Acid Ester 유도체의 합성

  • Nam, Seung-Ok (Medicinal Chemistry Laboratory, Department of Life and Nanopharmaceutical Science, Kyung Hee University) ;
  • Kim, Dong-Han (Medicinal Chemistry Laboratory, Department of Life and Nanopharmaceutical Science, Kyung Hee University) ;
  • Lee, Yong-Sup (Medicinal Chemistry Laboratory, Department of Life and Nanopharmaceutical Science, Kyung Hee University)
  • 남승옥 (경희대학교 약학대학 나노의약생명과학과 의약화학실) ;
  • 김동한 (경희대학교 약학대학 나노의약생명과학과 의약화학실) ;
  • 이용섭 (경희대학교 약학대학 나노의약생명과학과 의약화학실)
  • Published : 2009.04.30
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Abstract

Dicaffeoyltartaric acid has a structural feature consisting of two caffeic acid units separated by tartaric acid linker and has been found to be a potent inhibitor of HIV-1 integrase and an antioxidant. In this study, bis(pyronyl)acrylic acid esters joined through a 5-membered ring as a linker were synthesized as the analogues of dicaffeoyltartaric acid.

Keywords

References

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