Tuberculosis and Respiratory Diseases

The Korean Academy of Tuberculosis and Respiratory Diseases (대한결핵및호흡기학회)
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Two Cases of Endobronchial Actinomycosis that were Cured by Operation and Short Term Antibiotics Therapy

수술 및 단기간의 항생제 투여로 완치된 기관지 방선균증 2예

  • Lee, Yong Kwan (Department of Internal Medicine, Soonchunhyang University College of Medicine) ;
  • Lee, Ho Sung (Department of Internal Medicine, Soonchunhyang University College of Medicine) ;
  • Oh, Mee Hye (Department of Pathology, Soonchunhyang University College of Medicine) ;
  • Choi, Jae Sung (Department of Internal Medicine, Soonchunhyang University College of Medicine) ;
  • Seo, Ki Hyun (Department of Internal Medicine, Soonchunhyang University College of Medicine) ;
  • Kim, Yong Hoon (Department of Internal Medicine, Soonchunhyang University College of Medicine) ;
  • Na, Ju Ock (Department of Internal Medicine, Soonchunhyang University College of Medicine) ;
  • Hwang, Hun Gyu (Department of Internal Medicine, Soonchunhyang University College of Medicine)
  • 이용관 (순천향대학교 의과대학 천안병원 내과학교실) ;
  • 이호성 (순천향대학교 의과대학 천안병원 내과학교실) ;
  • 오미혜 (순천향대학교 의과대학 천안병원 병리학교실) ;
  • 최재성 (순천향대학교 의과대학 천안병원 내과학교실) ;
  • 서기현 (순천향대학교 의과대학 천안병원 내과학교실) ;
  • 김용훈 (순천향대학교 의과대학 천안병원 내과학교실) ;
  • 나주옥 (순천향대학교 의과대학 천안병원 내과학교실) ;
  • 황헌규 (순천향대학교 의과대학 천안병원 내과학교실)
  • Received : 2008.05.30
  • Accepted : 2008.07.08
  • Published : 2008.08.30
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Abstract

Endobronchial actinomycosis is a rare chronic suppurative granulomatous infection of the bronchus, and this is sometimes related with a foreign body or a broncholith. The traditional treatment of endobroncial actinomycosis is intravenous antibiotics for 2 to 6 weeks and then oral antibiotics therapy for 6 to 12 months. We report here on 2 cases of endobronchial actinomycosis that were associated with a broncholith and a foreign body, respectively. Surgery followed by short term antibiotics therapy for only 20 days and 34 days, respectively, was effective as treatment for the endobronchial actinomycosis in our cases. After treatment, there were no complications or recurrence during the following period. We suggest that short term antibiotics therapy combined with a surgical operation might be effective as treatment for primary endobronchial actinomycosis, and especially when this illness is combined with a foreign body or a broncholith, as compared with traditional long term antibiotic therapy.

저자 등은 수술 후 단기간의 항생제 치료로 완치된 기관지 방선균증 2예를 경험하였기에 보고하는 바이다.

Keywords

References

  1. Brown JR. Human actinomycosis: a study of 181 subjects. Hum Pathol 1973;4:319-30. https://doi.org/10.1016/S0046-8177(73)80097-8
  2. Hsieh MJ, Liu HP, Chang JP, Chang CH. Thoracic actinomycosis. Chest 1993;149:366-70.
  3. Russo TA. 156. Actinomycosis. In: Fauci AS, Braunwald E, Kasper DL, Hauser SL, Longo DL, Jameson JL, editors. Harrison's principles of internal medicine. 17th ed. New York: McGraw hill; 2008. p. 996-9.
  4. Dalhoff K, Wallner S, Finck C, Gatermann S, Wiessmann KJ. Endobronchial actinomycosis. Eur Respir J 1994;7: 1189-91.
  5. Choi JC, Koh WJ, Kwon YS, Ryu YJ, Yu CM, Jeon KM, et al. Diagnosis and treatment of endobroncial actinomycosis. Tuberc Respir Dis 2005;58:576-81. https://doi.org/10.4046/trd.2005.58.6.576
  6. Park JO, Ryu JW, Park S, Kim SH, Seo PW. Broncholithiasis caused by actinomycosis. Korean J Thorac Cardiovasc Surg 2006;39:236-9.
  7. Slade PR, Slesser BV, Southgate J. Thoracic actinomycosis. Thorax 1973;28:73-85. https://doi.org/10.1136/thx.28.1.73
  8. Goetz MB, Finegold SM. Actinomycosis. In: Murray FJ, Nadel JA, editors. Textbook of respiratory medicine. 3rd ed. Philadelphia: W.B.Saunders; 2000. p. 1020-2.
  9. Dicpinigaitis PV, Bleiweiss IJ, Krellenstein DJ, Halton KP, Teirstein AS. Primary endobronchial actinomycosis in association with foreign body aspiration. Chest 1992; 101:283-5. https://doi.org/10.1378/chest.101.1.283
  10. Ho JC, Ooi GC, Lam WK, Lam B, Cheung TF, Tsang KW. Endobronchial actinomycosis associated with a foreign body. Respirology 2000;5:293-6. https://doi.org/10.1046/j.1440-1843.2000.00261.x
  11. Harvey JC, Cantrell JR, Fisher AM. Actinomycosis: its recognition and treatment. Ann Intern Med 1957;46: 868-85. https://doi.org/10.7326/0003-4819-46-5-868
  12. Seo JB, Lee JW, Ha SY, Park JW, Jeong SH, Park GY. Primary endobronchial actinomycosis associated with broncholithiasis. Respiration 2003;70:110-3. https://doi.org/10.1159/000068425
  13. Hong SB, Kim WS, Lee JH, Bang SJ, Shim TS, Lim CM, et al. Clinical study on thoracic actinomycosis. Tuberc Respir Dis 1998;45:1058-66. https://doi.org/10.4046/trd.1998.45.5.1058
  14. Yu SE, Ju K, Song SH, Kim CH. A case report of primary endobronchial actinomycosis. Korean J Bronchoesophagol 2002;8:56-60.
  15. Skoutelis A, Petrochilos J, Bassaris H. Successful treatment of thoracic actinomycosis with ceftriaxone. Clin Infect Dis 1994;19:161-2. https://doi.org/10.1093/clinids/19.1.161
  16. Jara FM, Toledo-Pereyra LH, Magilligan DJ Jr. Surgical implications of pulmonary actinomycosis. J Thorac Cardiovasc Surg 1979;78:600-4.
  17. Park K, Kwon JB, Lee JH. Thoracic actinomycosis. Korean J Thorac Cardiovasc Surg 2005;38:50-5.