Journal of the Society of Cosmetic Scientists of Korea (대한화장품학회지)

Society of Cosmetic Scientists of Korea (대한화장품학회)
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Study on the Anti-inflammatory Effect of Polysaccharide Extract from Acyranthes bidentata

우슬 다당 추출물의 항염 효과에 관한 연구

  • 이대우 ((주)참존 기술원 응용연구소) ;
  • 김영진 ((주)참존 기술원 응용연구소) ;
  • 김영실 ((주)참존 기술원 응용연구소) ;
  • 엄상용 ((주)참존 기술원 응용연구소) ;
  • 김종헌 ((주)참존 기술원 응용연구소)
  • Published : 2008.03.31
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Abstract

Acyranthes bidentata has been used as anti-arrthritic, aphrodisiac, anti-viral, anti-spasmodic, anti-hypertensive, anti-coagulant and anti-tumor agent. In this study, we evaluated anti-inflammatory effect of polysaccharide extract from Acyranthes bidentata. Acyranthes bidentata polysaccaride decreased $IL-1{\alpha}$, IL-6, COX-2, and total NO synthesis. Our results point to the potential use of Acyranthes bidentata polysaccaride as a cosmeceutical agent for inflammatory cutaneous symptoms.

우슬(Acyranthes bidentata)은 항관절염(anti-arrthritic), 최음(aphrodisiac), 항바이러스(anti-viral), 항경련(anti-spasmodic), 항고혈압(anti-hypertensive), 항응고(anti-coagulant) 그리고 항암(anti-tumor)효과에 사용되어 왔다. 본 연구는 우슬 추출물로부터 분리한 다당 추출물의 화장품 원료로서의 특성을 알아보기 위하여 항염 효과와 관련된 다양한 실험을 실시하였다. 우슬 다당 추출물을 대상으로 실험한 결과 항염($IL-1{\alpha}$, IL-6, COX-2 그리고 total NO 생성 억제) 효과를 나타내었다.

Keywords

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