Browse > Article

Study on the Anti-inflammatory Effect of Polysaccharide Extract from Acyranthes bidentata  

Lee, Dae-Woo (R&D Center, Charmzone)
Kim, Young-Jin (R&D Center, Charmzone)
Kim, Young-Sil (R&D Center, Charmzone)
Eom, Sang-Yong (R&D Center, Charmzone)
Kim, Jong-Heon (R&D Center, Charmzone)
Publication Information
Journal of the Society of Cosmetic Scientists of Korea / v.34, no.1, 2008 , pp. 37-42 More about this Journal
Abstract
Acyranthes bidentata has been used as anti-arrthritic, aphrodisiac, anti-viral, anti-spasmodic, anti-hypertensive, anti-coagulant and anti-tumor agent. In this study, we evaluated anti-inflammatory effect of polysaccharide extract from Acyranthes bidentata. Acyranthes bidentata polysaccaride decreased $IL-1{\alpha}$, IL-6, COX-2, and total NO synthesis. Our results point to the potential use of Acyranthes bidentata polysaccaride as a cosmeceutical agent for inflammatory cutaneous symptoms.
Keywords
Acyranthes bidentata; anti-inflammation$IL-1{\alpha}$; IL-6; COX-2;
Citations & Related Records
Times Cited By KSCI : 6  (Citation Analysis)
연도 인용수 순위
1 S. T. Lee and Y. A. Chae, Cultivation of the medicinal plant, 159, Hyangmonsa, Seoul (1996)
2 I. H. Park, S. R. Lee, S. D. Lee, and W. S. Song, Cultivation of the medicinal plant, 281, Sunjin Munhwasa, Seoul (1993).
3 Z. E. Selvanayagam, S. G. Gnanavendan, K. Balakrishnan, and R. B. Rao, Antinake venom botanicals from Ethnomedicine, J. Herbs Spices Med. Plants, 2, 45 (1994)
4 P. Kim, K. I. Hyeon, J. Y. Chung, S. S. Yoon, H. C. Kang, S. H. Park, K. I. Ko, and K. H. Kim, A low irritant liquid cleanser composition developed by multi-screening methods, J. Soc. Cosmet. Scientists Korea, 31(1), 51 (2005)   과학기술학회마을
5 K. Rajnarayana, R. M. Sripal, and M. R. Chaluvadi, Bioflavonoids classification, pharmacological, biochemical effects and therapeutic potential, Indian J. Pharmacol., 33, 2 (2001)
6 A. C. Mitaine-Offer, A. Marouf, C. Pazza, T. C. Khanh, B. Chauffert, and M. A. Lacaille-Dubois, I. Bidentatoside, A new triterpene saponin from Achyranthes bidentata, J. Nat. Prod., 64(2), 243 (2001)   DOI   ScienceOn
7 K. A. Kim, J. S. Lee, H. J. Park, J. W. Kim, C. J. Kim, I. S. Shim, S. M. Han, and S. Lim, The inhibitory effect of Achyranthes bidentata radix extracts on cytochrome P450 catalyzed reactions in human liver microsomes, J. Korean Oriental Med., 24(2), 40 (2003)   과학기술학회마을
8 T. A. Wolfe and J. F. Dasta, Use of nitric oxide synthase inhibitors as a novel treatment for septic shock, Ann. Pharmacother., 29, 36 (1995)   DOI   PUBMED
9 C. S. Yook, Pharmacology, 24, Hakchangsa, Seoul (1993)
10 O. R. Koch, G. Pani, S. Borrello, R. Colavitti, A. Cravero, S. Farre, and T. Galeotti, Oxidative stress and antioxidant defenses in ethanol-induced cell injury, Molecular Aspects of Medicine, 25, 191 (2004)   DOI   ScienceOn
11 J. S. Oh, G. Y. Im, J. Teong, H. C. Lee, and S. S. Chung, Effect of steroid hormone on the expression of cytokine genes in the peritoneal macrophages of mouse, J. Korean Cancer Assoc., 26, 607 (1994)
12 L. J. Ignarro, G. M. Buga, K. S. Wood, R. E. Byms, and G. Chaudhuri, Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide, Proc. Natl. Acad. Sci. USA, 84(24), 9265 (1987)
13 E. A. Seo and H. C. Moon, Effects of radix Achyranthis bidentatae extract on proliferation and differentiation in human osteoblast-like cells, Korean J. Oriental Physiology & Pathology, 18(6), 1821 (2004)   과학기술학회마을
14 T. Kishimoto, The biology of interleukin 6, Blood, 74, 1 (1989)   PUBMED
15 N. McCartcy-Francis, J. B. Allen, D. E. Mizel, J. E. Albina, Q. W. Xie, C. F. Nathan, and S. M. Wahl, Suppression of arthritis by and inhibitor of nitric oxide synthase, J. Exp. Med., 178, 749 (1993)   DOI   ScienceOn
16 R. Radi, J. S. Beckman, K. M. Bush, and B. A. Freeman, Peroxynitrite oxidation of sulfhydryls. The cytotoxic potential of superoxide and nitric oxide, J. Biol. Chem., 266, 4244 (1991)   PUBMED
17 R. K. Singh and B. L. Pandey, Further study of anti-inflammatory effects of Abies pindrow, Phytotherary Research, 11, 535 (1997)   DOI   ScienceOn
18 R. Romero, C. Avila, U. Santhanam, and P. B. Sehagal, Amniotic fluid interleukin 6 in preterm labor- associated with infractional, J. Clin. Invest., 85, 1392 (1990)   DOI   ScienceOn
19 Y. J. Surh, Anti-tumor promoting potential of selected spice ingredients with antioxidative and anti-inflammatory activities : a short review, Food Chem. Toxicol., 40(8), 1091 (2002)   DOI   ScienceOn
20 D. R. Hahn and M. W. Lee, Studies on the constituents of Achyranthis radix (I) - oleanolic acid bisdesmoside from the root, J. Pharm. Soc. Korea, 35(6), 457 (1991)   과학기술학회마을
21 J. Pfeilschifter, W. Eberhardt, R. Hummel, D. Kunz, H. Muhl, D. Nitsch, C. Pluss, and G. Walker, Therapeutic strategies for the inhibition of inducible nitiric oxide synthase potential for a novel class of anti-inflammatory agents, Cell Biol. Int., 20, 51 (1996)   DOI   ScienceOn
22 P. S. Ratra and K. C. Misra, Seasonal variation in chemical composition of Achyranthes aspera and A. bidentata, Indian Forester, 96, 372 (1970)
23 G. Bishit, H. Snadhu, and S. Verma, Constituents of Achyranthes bidentata, Fitoterapia, 64, 85 (1993)
24 K. S. Lee, J. I. Lee, J. K. Lee, J. Lee, G. D. Kim, and M. J. Oh, Inhibition effect of Achyranthes japonica N. root extract on cathepsin B, Korean J. Food Preserv., 12(3), 275 (2005)   과학기술학회마을
25 D. Salvemini, T. P. Misko, J. L. Masferrer, K. Seibert, M. G. Currie, and P. Needleman, Nitric oxide activates cyclooxygenase enzymes, Proc. Natl. Acad. Sci. USA, 90, 7240 (1993)
26 H. G. Kang, J. W. Hong, H. J. Han, Y. Y. Hwang, J. Y. Jeong, and K. N. Lee, Effects of methanol extract of radix Achyranthis bidentatae on cadmium inhalation, Korean J. Oriental Physiology & Pathology, 18(6), 1784 (2004)   과학기술학회마을
27 Y. J. Surh, K. S. Chun, H. H. Cha, S. S. Han, Y. S. Keum, K. K. Park, and S. S. Lee, Molecular mechanisms underlying chemopreventive activities of anti-inflammatory phytochemicals : down-regulation of COX-2 and iNOS through supression of NF-kappa B activation, Mutat. Res., 480, 243 (2001)   PUBMED
28 Y. S. Chang, C. Y. Chen, and L. K. Ko, Studies on the chemical constituents of Achyranthes bidentata Blume, J. Chin. Med., 8, 177 (1997)
29 J. A. Angus and T. M. Cocks, Endothelium-derived relaxing factor, Pharmacol. Ther., 41, 303 (1989)   DOI   ScienceOn