Analytical Science and Technology (분석과학)

The Korean Society of Analytical Sciences (한국분석과학회)
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Process analytical technology (PAT): new paradigm for the state-of-the-art analytical technology

공정분석기술: 첨단 분석기술의 새로운 패러다임

  • 김종윤 (한국원자력연구원 원자력화학연구부) ;
  • 박용준 (한국원자력연구원 원자력화학연구부) ;
  • 연제원 (한국원자력연구원 원자력화학연구부) ;
  • 우영아 ((주) 한국유나이티드제약 제제연구소) ;
  • 김효진 (동덕여자대학교 약학과) ;
  • 송규석 (한국원자력연구원 원자력화학연구부)
  • Received : 2008.08.19
  • Accepted : 2008.10.06
  • Published : 2008.10.25
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Abstract

Process analytics has been already widely utilized in a large-scale continuous production line such as petroleum industries for several decades. Although the process analytics has a long history, a concept of "Process Analytical Technology (PAT)" has been rapidly adopted as a new paradigm for the process monitoring in the production process of various industries. In this review, current status and recent developments of PAT in various research bodies have been introduced, including the introduction of various types of analytical instruments, chemometrics tools, and perspectives and future applications of PAT as well as the fundamentals on PAT such as terminology and its historical background.

이미 석유화학산업 등 대규모 산업공정에서 널리 활용되고 있는 공정분석화학 및 공정분석기술의 역사는 오래되었지만, 최근 "공정분석기술(Process Analytical Technology: PAT)"의 새로운 개념이 매우 빠르게 일부 산업분야의 생산공정에 보급되고 있다. 본 총설에서는 이미 오래 전부터 대규모 연속식 생산라인에서 널리 활용되어 왔던 공정분석화학 및 공정분석기술의 신개념 첨단 분석기술로서의 태동 배경과 용어 정의 등을 명확히 하였다. 또한, 공정최적화를 위한 공정분석화학 혹은 공정분석기술의 기본개념, 계량화학 등의 공정분석화학 핵심요소, 국내외 산/학/연의 기술 및 활동 현황 등에 관하여 다루었고, PAT에서 주로 활용되고 있는 공정분석기기의 종류와 현황, 그리고 미래 유망기술 및 활용분야에 대해서도 소개하였다.

Keywords

Acknowledgement

Supported by : 과학기술부

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