동물실험용 골융합 임플란트 시스템 개발

Development of the Osseo-integrated Implant system for Laboratory Animals

  • 배태수 (산재의료관리원 재활공학연구소 인체공학연구팀) ;
  • 허현 (산재의료관리원 재활공학연구소) ;
  • 김신기 (산재의료관리원 재활공학연구소) ;
  • 문무성 (산재의료관리원 재활공학연구소) ;
  • 안재용 (관동대학교 의과대학) ;
  • 홍성란 (관동대학교 의과대학)
  • 발행 : 2007.10.01

초록

The novel implant system was developed using osseo-integration technology which enable amputee to overcome skin troubles in use of previous socket system and was evaluated in view of biomechanics, radiology, histology, and pathology. The osseo-integrated implants were designed and manufactured using CT image of canine's tibia and were applied to laboratory animals (canines). The follow-up studies were performed for 24 months with 10 canines. In radiology examination, we found that the relative low strain distribution caused medial and posterior bone resorption and then we verified them by biomechanical testing. In histological approach, the complete osseo-integration was observed through the activity of osteoblast cells around bone-implant interface and the radial outer region of bone due to peristeum reaction. Lastly in pathological aspect, the evidence of superficial infection was detected but that of deep infection was not. Therefore it is thought that infection problem will be overcome by immunity of body and good hygiene.

키워드

참고문헌

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