Asian-Australasian Journal of Animal Sciences

Asian Australasian Association of Animal Production Societies (아세아태평양축산학회)
권호 표지
DOI QR코드

DOI QR Code

Skin Deiodinase Profiles after Melatonin Manipulated in Chinese Inner Mongolia Cashmere Goats

  • Yue, Chunwang (College of Animal Science and Technology, China Agricultural University) ;
  • Du, Lixin (Institute of Animal Science Chinese Academy of Agricultural Sciences) ;
  • Zhu, Xiaoping (College of Animal Science and Technology, China Agricultural University) ;
  • Kong, Xianghao (College of Animal Science and Technology, Hebei North University) ;
  • Zhang, Wei (College of Animal Science and Technology, China Agricultural University) ;
  • Jia, Zhihai (College of Animal Science and Technology, China Agricultural University)
  • Received : 2007.01.10
  • Accepted : 2007.04.23
  • Published : 2007.10.01
Download PDF
⟨ Previous Next ⟩

Abstract

The roles of melatonin in the control of deiodinase (MD) activity in cashmere goat skin and associated cashmere fibre growth were investigated. Eighteen half-sib Chinese Inner Mongolia cashmere wethers were allocated randomly to two groups (n = 9/group). One group was implanted subcutaneously with melatonin (2 mg/kg BW) at three 2-monthly intervals while the other group served as a control. All goats were maintained under natural photoperiodic conditions and were grazed on natural pasture. The plasma melatonin concentration showed a significant difference (p<0.01) between the implant group (M) and the control group (C) but plasma $T_4$ (or $T_3$) showed no significant difference (p>0.05). The monodeiodinase type II (MDII) activity in skin tended to increase gradually from the summer solstice to November. During July and August, the activity of MDII for the M group was higher (p<0.05) than that of the C group; also during this period, there was a significant positive correlation between MDII activity of skin and cashmere fibre growth rate. The monodeiodinase type III (MDIII) activity and the ratio of MDIII and MDII tended to decrease from the summer solstice to November. The ratio of MDIII and MDII for the M group was lower (p<0.05) than that of the C group in July and August. The cashmere fibre growth rate of the M group was significantly greater than that of the C group in July (p<0.01), August (p<0.001) and September (p<0.05). The cashmere fibre diameter and guard hair and body weight were not influenced (p>0.05) by melatonin implantation. The results demonstrate that melatonin plays an important role in the regulation of skin MD activity. Simultaneously, the cashmere fibre elongation stimulated by melatonin may result from enhanced MDII activity during a period of two months after melatonin treatment.

Keywords

References

  1. Bai, J. Y., Q. Zhang, J. Q. Li, E. J. Dao and X. P. Jia. 2006. Estimates of Genetic Parameters and Genetic Trends for Production Traits of Inner Mongolian White Cashmere Goat. Asian-Aust. J. Anim. Sci. 19:13-18.
  2. Beckett, G. J. and J. R. Arthur. 1994. The iodothyronine deiodinases and 5'-deiodination. In: (Ed. M. C. Sheppard and P. M. Stewart). Bailliere's Clin. Endocr. Metab. 8:285-304. https://doi.org/10.1016/S0950-351X(05)80253-8
  3. Chen, S. L., M. H. Li, Y. J. Li, S. H. Zhao, C. Z. Yu, M. Yu, B. Fan and K. Li. 2001. RAPD Variation and Genetic Distances among Tibetan, Inner Mongolia and Liaoning Cashmere Goats Asian-Aust. J. Anim. Sci. 14:1520-1522. https://doi.org/10.5713/ajas.2001.1520
  4. Dicks, P., A. J. F. Russel and G. A. Lincoln. 1994. The role of prolactin in the reactivation of hair follicles and the spring moult in goats. J. Endocr. 143:441-448. https://doi.org/10.1677/joe.0.1430441
  5. Dicks, P., A. J. F. Russel and G. A. Lincoln. 1995. The effect of melatonin implants administered from December until April, on plasma prolactin, triiodothyronine and thyroxine concentrations and on the timing of the spring moult in cashmere goats. Anim. Sci. 60:239-247. https://doi.org/10.1017/S1357729800008407
  6. Dicks, P., C. J. Morgan, P. J. Morgan, D. Kelly and L. M. Williams. 1996. The locanlisation and characterisation of insulin-like growth factor-I (IGF-I) receptors and the investigation of melatonin receptors on the hair follicles of seasonal and nonseasonal fibre-producing goats. J. Endocr. 151:55-63. https://doi.org/10.1677/joe.0.1510055
  7. Hans, W. and N. K. Duong. 2004. Effects of Ensiled Cassava Tops on Rumen Environment Parameters, Thyroid Gland Hormones and Liver Enzymes of Cows Fed Urea-treated Fresh Rice Straw. Asian-Aust. J. Anim. Sci. 17:936-941. https://doi.org/10.5713/ajas.2004.936
  8. Ibraheem, M., H. Galbraith, J. Scaife and S. Rwen. 1994. Growth of secondary hair follicles on the Cashmere goat in vitro and their response to prolactin and melatonin. J. Anat. 1:135-142.
  9. Jia, Z. H., T. H. The and M. An. 1996. Effects of exogenous melatonin on the productivity of cashmere goats. International Academic Publishers, Vi International Conference on Goats. 2:890-893.
  10. Kloren, W. R. L., B. W. Norton and M. J. Waters. 1993. Fleece growth in Australian cashmere goats. III. The seasonal patterns of cashmere and hair growth, and association with growth hormone, prolactin and thyroxine in blood. Aust. J. Agric. Res. 44:1035-1050. https://doi.org/10.1071/AR9931035
  11. Lohakare, J. D., A. K. Pattanaik and S. A. Khan. 2006. Effect of Dietary Protein Levels on the Performance, Nutrient Balances, Metabolic Profile and Thyroid Hormones of Crossbred Calves. Asian-Aust. J. Anim. Sci. 19:1588-1596. https://doi.org/10.5713/ajas.2006.1588
  12. Nixon, A. J., V. J. Choy, A. L. Parry and A. J. Pearson. 1993. Fiber growth initiation in hair follicles of goats treated with melatonin. J. Exp. Zool. 1:47-56.
  13. Rajendran, D., A. K. Pattanaik, S. A. Khan and S. P. S. Bedi. 2001. Iodine Supplementation of Leucaena leucocephala Diet for Goats. II. Effects on Blood Metabolites and Thyroid Hormones. Asian-Aust. J. Anim. Sci. 14:791-796. https://doi.org/10.5713/ajas.2001.791
  14. Rhind, S. M. and S. R. Mcmillen. 1995. Seasonal patterns of secondary fibre growth, moulting and hair follicle activity in Siberian and Icelandic${\times}$Scottish feral goats offered high and liw levels of dietary protein. Small Rumin. Res. 17:69-76.
  15. Rhind, S. M., C. E. Kyle and E. I. Duff. 2004a. Effects of season and of manipulation of circulating prolactin concentrations on deiodinase activity in cashmere goat skin. Aust. J. Agric. Res. 55:211-221. https://doi.org/10.1071/AR03119
  16. Rhind, S. M. and C. E. Kyle. 2004b. Skin deiodinase profiles and associated patterns of hair follicle activity in cashmere goats of contrasting genotypes. Aust. J. Agric. Res. 55:443-448. https://doi.org/10.1071/AR03184
  17. Santiago-Moreno, J., A. Lopez-Sebastian, A. Campoa, A. Gonzalez-Bulnes, R. Picazo and A. Gomez-Brunet. 2004. Effect of constant-release melatonin implants and prolonged exposure to a long day photoperiod on prolactin secretion and hair growth in mouflon (Ovis gmelini musimon). Dom. Anim. En. 26:303-314. https://doi.org/10.1016/j.domaniend.2003.12.004
  18. Santiago-Moreno, J., A. Gómez-Brunet, A. Gonzalez-Bulnes, A. Toledano-Díaz, B. Malpaux and A. López-Sebastiάn. 2005. Differences in reproductive pattern between wild and domestic rams are not associated with inter-specific annual variations in plasma prolactin and melatonin concentrations. Dom. Anim. En. 28:416-429. https://doi.org/10.1016/j.domaniend.2005.02.002
  19. SAS. 1999. SAS/STAT User'guide, (Release 8.2). SAS Inst. Inc., Cary, NC.
  20. Teh, T. H., Z. H. Jia, K. D. Odgen and G. I. Newton. 1991. The effects of photoperiod and melatonin implant on cashmere production. J. Anim. Sci. 69:496 (Abstr).
  21. Vanecek, J. 1998. Cellular Mechanisms of Melatonin Action. Physiol. Rev. 78:687-721. https://doi.org/10.1152/physrev.1998.78.3.687
  22. Villar, D., S. R. McMillen, P. Dicks and M. Rhind. 1999. The effects of bovine somatotropin on hair follicle activity and cashmere fibre growth in goats. Aust. J. Agric. Res. 50:1365-1373. https://doi.org/10.1071/AR99028
  23. Villar, D., S. R. McMillen, P. Dicks and S. M. Rhind. 2000a. The roles of thyroid hormones and prolactin in the control of fibre moult and associated changes in hair follicle activities in cashmere goats. Aust. J. Agric. Res. 51:407-414. https://doi.org/10.1071/AR99104
  24. Villar. D., F. Nicol, J. R. Arthur, P. Dicks, A. Cannavan, D. G. Kennedy and S. M. Rhind. 2000b. Type II and type III monodeiodinase activites in the skin of untreated and propylthiouracil-treated cashmere goats. Res. Vet. Sci. 68:119-123. https://doi.org/10.1053/rvsc.1999.0344
  25. Wang, L. F., D. X. Lu, H. Z. Sun, X. Y. Zhao and D. San. 2006. Effects of photoperiod and melatonin on nitrogen partitioning and cashmere growth in Inner Mongolia White Cashmere Goats. Agric. Sci. Chin. 39:1004-1010 (Chinese).
  26. Zhou, H. M., D. Allain, J. Q. Li, W. G. Zhang and X. C. Yu. 2003. Effects of non-genetic factors on production traits of Inner Mongolia cashmere goats in China. Small Rumin. Res. 47:85-89. https://doi.org/10.1016/S0921-4488(02)00246-8

Cited by

  1. Dietary Iodine and Selenium Affected the mRNA Expression Levels of Skin Monodeiodinase (II, III) in Liaoning Cashmere Goats vol.151, pp.3, 2013, https://doi.org/10.1007/s12011-012-9583-6
  2. Effects of melatonin implantation on cashmere yield, fibre characteristics, duration of cashmere growth as well as growth and reproductive performance of Inner Mongolian cashmere goats vol.6, pp.1, 2015, https://doi.org/10.1186/s40104-015-0023-2
  3. Melatonin and cashmere growth in Inner Mongolian cashmere goats vol.96, pp.2, 2016, https://doi.org/10.1139/cjas-2015-0018
  4. Expression of Prolactin Receptor mRNA after Melatonin Manipulated in Cashmere Goats Skin during Cashmere Growth vol.23, pp.10, 2007, https://doi.org/10.5713/ajas.2010.10010