Natural Product Sciences

The Korean Society of Pharmacognosy (한국생약학회)
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Norsesquiterpene and Steroid Constituents of Humulus japonicus

  • Yu, Byung-Chul (Natural Products Laboratory, College of Pharmacy, Sungkyunkwan University) ;
  • Yang, Min-Cheol (Natural Products Laboratory, College of Pharmacy, Sungkyunkwan University) ;
  • Lee, Kyu-Ha (Natural Products Laboratory, College of Pharmacy, Sungkyunkwan University) ;
  • Kim, Ki-Hyun (Natural Products Laboratory, College of Pharmacy, Sungkyunkwan University) ;
  • Lee, Kang-Ro (Natural Products Laboratory, College of Pharmacy, Sungkyunkwan University)
  • Published : 2007.12.31
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Abstract

Five steroids and two norsesquiterpene glycosides were isolated from the methanol extract of H. japonicus. Their structures were determined by means of physio-chemical and spectral data to be friedelin (1), stigmast-5-en-3-${\beta}$-ol (${\beta}$-sitosterol) (2), 7-keto-${\beta}$-sitosterol (3), 6${\beta}$-hydroxy-4-stigmasten-3-one (4), 7${\alpha}$-hydroxy-${\beta}$-sitosterol (5), 3-hydroxy-4,4-dimethyl-4-butyrolactone (6), daucosterol (7), (6S, 9S)-roseoside (8), and (9S)-drummondol-9-O-${\beta}$-D-glucopyranoside (spinoside B) (9). The compounds 1, 3, 4, and 6 - 9 were first isolated from this plant source.

Keywords

References

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