Journal of the Korean Institute of Electrical and Electronic Material Engineers (한국전기전자재료학회논문지)

The Korean Institute of Electrical and Electronic Material Engineers (한국전기전자재료학회)
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A Study on Gene Detection using Non-labeling DNA

  • Choi Yong-Sung (Department of Electrical Engineering, Dongshin University) ;
  • Lee Kyung-Sup (Department of Electrical Engineering, Dongshin University) ;
  • Kwon Young-Soo (Department of Electrical Engineering, Donga University)
  • Published : 2006.10.01
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Abstract

This research aims to develop the multiple channel electrochemical DNA chip using microfabrication technology. At first, we fabricated a high integration type DNA chip array by lithography technology. Several probe DNAs consisting of thiol group at their 5-end were immobilized on the gold electrodes. Then target DNAs were hybridized and reacted. Cyclic voltammetry showed a difference between target DNA and control DNA in the anodic peak current values. Therefore, it is able to detect a plural genes electrochemically after immobilization of a plural probe DNA and hybridization of non-labeling target DNA on the electrodes simultaneously. It suggested that this DNA chip could recognize the sequence specific genes.

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References

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