Journal of Physiology & Pathology in Korean Medicine (동의생리병리학회지)

The Physiological Society of Korean Medicine and The Society of Pathology in Korean Medicine (대한동의생리학회·한의병리학회)
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Effect of Water Extract of KH-304 on Anti-oxidant and Erectile dysfunction in Old Rat

KH-304의 항산화효과 및 Old rat model 에서의 Erectile dysfunction에 미치는 영향

  • 이은정 (주) KMSI 부설 한국의과학연구소) ;
  • 이현지 (주) KMSI 부설 한국의과학연구소) ;
  • 김희석 (주) KMSI 부설 한국의과학연구소) ;
  • 황성완 (주) KMSI 부설 한국의과학연구소) ;
  • 황성연 (주) KMSI 부설 한국의과학연구소)
  • Published : 2006.08.25
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Abstract

The fallowing are the result of the experimental studies of KH-304 on the penile nitric oxide synthase (NOS) activity, SOD and the level of blood testosterone in old rat. KH-304 was tested for the expression and activity of eNOS, nNOS, SOD/Mn, caveol in-1, 3 in penis of old-rat. The penile expression level of the five enzyme were increased significantly after oral administration of the KH-304 100mg/kg for 100ays and the concentration of testosterone in the blood were increased. In vitro, the effect of SOD and free radical scavenging were increased significantly. Conclusively, KH-304 is capable of improving of sexual ability in old-rat.

Keywords

References

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