대한두경부종양학회지 (Korean Journal of Head & Neck Oncology)

  • 제21권1호
  • /
  • Pages.48-52
  • /
  • 2005
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  • 1229-5183(pISSN)
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  • 2586-2553(eISSN)
대한두경부종양학회 (The Korean Society for Head and Neck Oncology)
권호 표지

경부와 종격동에 발생한 캐슬만씨 병(Castleman's Disease)

Castleman's Disease of the Neck and Mediastinum

  • 남기현 (연세대학교 의과대학 외과학교실) ;
  • 최현호 (연세대학교 의과대학 외과학교실) ;
  • 임치영 (연세대학교 의과대학 외과학교실) ;
  • 이잔디 (연세대학교 의과대학 외과학교실) ;
  • 김승일 (연세대학교 의과대학 외과학교실) ;
  • 장항석 (연세대학교 의과대학 외과학교실) ;
  • 홍순원 (연세대학교 의과대학 병리학교실) ;
  • 박정수 (연세대학교 의과대학 외과학교실)
  • Nam Kee-Hyun (Department of Surgery, Yonsei University College of Medicine) ;
  • Choi Hyun-Ho (Department of Surgery, Yonsei University College of Medicine) ;
  • Lim Chi-Young (Department of Surgery, Yonsei University College of Medicine) ;
  • Lee Jan-Dee (Department of Surgery, Yonsei University College of Medicine) ;
  • Kim Seung-Il (Department of Surgery, Yonsei University College of Medicine) ;
  • Chang Hang-Seok (Department of Surgery, Yonsei University College of Medicine) ;
  • Hong Soon-Won (Department of Pathology, Yonsei University College of Medicine) ;
  • Park Cheong-Soo (Department of Surgery, Yonsei University College of Medicine)
  • 발행 : 2005.05.01
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초록

Objectives: Castleman's disease(CD) is a lymphoproliferative disorder of unknown etiology. To elucidate the clinicopathologic characteristics of CD, we retrospectively reviewed our experience. Methods: Fifteen patients with CD of the neck and mediastinum were identified. Patients were divided into two groups: group I had an unicentric CD and group II had multicentric CD. The histology of CD was divided into 3 subtypes: hyaline-vascular(HV), plasma cell(PC), and mixed. Results: The study included 12 cases of group I, 3 cases of group II in the clinical aspect and 10 cases with HV, 3 cases with PC, 2 cases with mixed type in the histologic aspect. Of group I patients who underwent complete surgical excision, all are currently free of disease. The clinical course of group II patients was variable. Of two patients with multicentric plasma cell CD who were treated, one remain free from disease and the other had a local recurrence in the neck. One patient with multicentric mixed CD died of disease after 30 months of presentation. Conclusion: Surgical resection is recommend for patients with the unicentric CD, regardless of histologic subtype. Patients with multicentric disease do not benefit from surgical resection and should be candidates for multimodality therapy.

키워드

참고문헌

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