대한본초학회지 (The Korea Journal of Herbology)

  • 제20권3호
  • /
  • Pages.19-27
  • /
  • 2005
  • /
  • 1229-1765(pISSN)
  • /
  • 2288-7199(eISSN)
대한본초학회 (The Korea Association of Herbology)
권호 표지

연교산과 구성약재에 대한 항암 및 항산화효과

Cytotoxicity and Antioxidant Activities of the Yeonkyo-san and Its ingredients

  • 이진태 (대구한의대학교 화장품약리학과) ;
  • 이창언 (대구한의대학교 화장품약리학과) ;
  • 손준호 (대구한의대학교 화장품약리학과) ;
  • 이진영 (대구한의대학교 화장품약리학과) ;
  • 박태순 (대구한의대학교 화장품약리학과) ;
  • 이인철 (대구한의대학교 화장품약리학과) ;
  • 천순주 (대구한의대학교 화장품약리학과) ;
  • 편정란 (대구한의대학교 화장품약리학과) ;
  • 지선영 (대구한의대학교 한의학과) ;
  • 조철훈 (한국원자력연구소 방사선연구원) ;
  • 안봉전 (대구한의대학교 화장품약리학과)
  • Lee, Jin-Tae (Dept. of Cosmeceutical Science, Daegu Haany University) ;
  • Lee, Chang-Eon (Dept. of Cosmeceutical Science, Daegu Haany University) ;
  • Son, Jun-Ho (Dept. of Cosmeceutical Science, Daegu Haany University) ;
  • Lee, Jin-Young (Dept. of Cosmeceutical Science, Daegu Haany University) ;
  • Park, Tae-Soon (Dept. of Cosmeceutical Science, Daegu Haany University) ;
  • Lee, In-Cheol (Dept. of Cosmeceutical Science, Daegu Haany University) ;
  • Cheon, Soon-Ju (Dept. of Cosmeceutical Science, Daegu Haany University) ;
  • Pyeon, Jeong-Ran (Dept. of Cosmeceutical Science, Daegu Haany University) ;
  • Jee, Seon-Young (Dept. of Oriental Medicine, Daegu Haany University) ;
  • Jo, Cheol-Hun (Advanced Radiation Technology Institute) ;
  • An, Bong-Jeun (Dept. of Cosmeceutical Science, Daegu Haany University)
  • 발행 : 2005.09.30
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초록

Objectives : The antioxidant activities of Yeonkyo-san and its ingredient were investigated for industrial application. Methods : We experimented radical scavenging effect, superoxide dismutase and cytotoxicity effect of various cancer cell. Results : The result were obtained as follows : Primary testing of cytotoxicity of Yeonkyo-san and ingredient was done for G361. B16F10, MDA and A549 cell lines. Yeonkyo-san and ingredient water extract, ethanol extract showed cytotoxicity of over 90% respectively against cell line. The electron donating ability(EDA) of water extract from the Yeonkyo-san was higher than 60%, ethanol extract from the Yeonkyo-san was over 80% at 1000 ppm. The electron donating ability(EDA) of water extract and ethanol extract from the Yeonkyo-san ingredients were increased as well. SOD-like activity was high as 75% in 700 ppm, it was increased. All the other samples showed less than 40% SOD-like activity. Conclusions : The results indicated that water extract and ethanol extract of Yeonkyo-san and ingredient can be used as a natural ingredient with biological functions in cosmetic and food composition.

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