대한본초학회지 (The Korea Journal of Herbology)

  • 제20권3호
  • /
  • Pages.51-58
  • /
  • 2005
  • /
  • 1229-1765(pISSN)
  • /
  • 2288-7199(eISSN)
대한본초학회 (The Korea Association of Herbology)
권호 표지

선방활명음의 항암 및 항산화효과 검증

Cytotoxicity and Physiological Activity of SunbangHwalmyung-um

  • 이진태 (대구한의대학교 화장품약리학과) ;
  • 이창언 (대구한의대학교 화장품약리학과) ;
  • 손준호 (대구한의대학교 화장품약리학과) ;
  • 이인철 (대구한의대학교 화장품약리학과) ;
  • 이진영 (대구한의대학교 화장품약리학과) ;
  • 박태순 (대구한의대학교 화장품약리학과) ;
  • 장민정 (대구한의대학교 화장품약리학과) ;
  • 송미애 (대구한의대학교 화장품약리학과) ;
  • 지선영 (대구한의대학교 한의학과) ;
  • 안봉전 (대구한의대학교 화장품약리학과)
  • Lee, Jin-Tae (Dept. of Cosmeceutical Science, Daegu Haany University) ;
  • Lee, Chang-Eon (Dept. of Cosmeceutical Science, Daegu Haany University) ;
  • Son, Jun-Ho (Dept. of Cosmeceutical Science, Daegu Haany University) ;
  • Lee, In-Cheol (Dept. of Cosmeceutical Science, Daegu Haany University) ;
  • Lee, Jin-Young (Dept. of Cosmeceutical Science, Daegu Haany University) ;
  • Park, Tae-Soon (Dept. of Cosmeceutical Science, Daegu Haany University) ;
  • Jang, Min-Jung (Dept. of Cosmeceutical Science, Daegu Haany University) ;
  • Song, Mi-Ae (Dept. of Cosmeceutical Science, Daegu Haany University) ;
  • Jee, Seon-Young (Dept. of Oriental Medicine, Daegu Haany University) ;
  • An, Bong-Jeun (Dept. of Cosmeceutical Science, Daegu Haany University)
  • 발행 : 2005.09.30
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초록

Objectives : The purpose of this research was physiological activities and investigate cytotoxicity of Sunbanghwalmyung-um extract. Methods : Physiological activity and a cytotoxicity were examined through the hot water and ethanol extracts from Sunbanghwalmyung-um and its ingredient. Results : The electron donating ability(EDA) was 66.9%, 71.3% in 1000 ppm water extract and ethanol extract. Above 90% from 1000 ppm ethanol extract showed a higher activities and it is Rhei Radix et Rhizoma, Lonicerae Flos, Gleditsiae Spina, Glycyrrhizae Radix, Myrrh. SOD-like activity was weak as 12.24%, 16.62% in 700 ppm. In water and ethanol extracts cytotoxicity were against G361, B16F10, MDA, A549, high cytotoxity over 70%. Rhei Radix et Rhizoma, Gleditsiae Spina, Trichosanthis Radix, Paeoniae Radix Rubra showed high cytotoxicity in water and ethanol extracts. Conclusions : We observed physiological activities and investigated cytotoxicity of Sunbanghwalmyung-um and its ingredients. The results also demonstrated in food or cosmetic industry.

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