DOI QR코드

DOI QR Code

Mild and Efficient Silylcyanation of Aldehydes Catalyzed by Zirconium Complex

  • Published : 2005.02.20

Abstract

An efficient method of addition of trimethylsilyl cyanide to aldehydes by employing a zirconium complex as the catalyst has been described. A variety of aromatic, aliphatic, cyclic and heterocyclic aldehydes has been converted into corresponding trimethylsilyl ethers in excellent yield within short reaction time.

Keywords

References

  1. Gregory., R. J. H. Chem. Rev. 1999, 99, 3649 https://doi.org/10.1021/cr9902906
  2. Weber, W. P. Silicon Reagents for Organic Synthesis; Springer: Berlin, 1983; pp 6-20
  3. The Chemistry of Organic Silicon Compounds; Patai, S., Rappoport, Z., Eds.; Wiley: Chichester, 1989
  4. Evans, D. A.; Truesdake, L. K.; Carroll, G. L. J. Chem. Soc. 1973, 2, 55
  5. Lidy, W.; Sundermeyer, W. Tetrahedron Lett. 1973, 9, 1449
  6. Kobayashi, S.; Tsuchiya, Y.; Mukaiyama, T. Chem. Lett. 1991, 4, 537
  7. Lidy, W.; Sundermeyer, W. Chem. Ber. 1973, 106, 587 https://doi.org/10.1002/cber.19731060224
  8. Whitesell, J. K.; Apodaca, R. Tetrahedron Lett. 1996, 37, 2525 https://doi.org/10.1016/0040-4039(96)00386-3
  9. Saravanan, P.; Vijaya, R.; Singh, V. K. Tetrahedron Lett. 1998, 39, 3823 https://doi.org/10.1016/S0040-4039(98)00594-2
  10. Jenner, G. Tetrahedron Lett. 1999, 40, 491 https://doi.org/10.1016/S0040-4039(98)02419-8
  11. Curini, M.; Epifan, F.; Marcotullio, M. C.; Rosati, O.; Rossi, M. Synlett 1999, 315
  12. Bandini, M.; Cozzi, P. G.; Melchiorre, P.; Umani-Roncohi, A. Tetrahedron Lett. 2001, 42, 3041 https://doi.org/10.1016/S0040-4039(01)00368-9
  13. Bandini, M.; Cozzi, P. G.; Garelli, A.; Melchiorre, P.; Umani-Ronchi, A. Eur. J. Org. Chem. 2002, 3243
  14. Shen, Y.; Feng, X.; Li, Y.; Zhang, G.; Jiang, Y. Synlett 2002, 793
  15. Chen, F.; Feng, X.; Qin, B.; Zhang, G.; Jiang, Y. Synlett 2003, 558
  16. Shen, Y.; Feng, X.; Li, Y.; Zhang, G.; Jiang, Y. Tetrahedron 2003, 59, 5667 https://doi.org/10.1016/S0040-4020(03)00908-6
  17. Kim, S. S.; Song, D. H. J. Orgnomet. Chem. 2004, in press
  18. Kim, S. S.; Rajagopal, G.; Song, D. H. J. Orgnomet. Chem. 2004, 689, 1734 https://doi.org/10.1016/j.jorganchem.2004.01.025
  19. Kim, S. S.; Rajagopal, G.; Kim, D. W.; Song, D. H. Synthetic Commun. 2004, 34(16), 2973 https://doi.org/10.1081/SCC-200026652
  20. Kim, S. S.; Song, D. H. Letter. Org. Chem. 2004, 1, 264 https://doi.org/10.2174/1570178043400884
  21. Evans, D. A.; Truesdale, L. K. Tetrahedron Lett. 1973, 49, 4929
  22. Takashi, O.; Tomoya, M.; Keisuke, T.; Hayato, I.; Keiji, M. Tetrahedron 2001, 57, 867 https://doi.org/10.1016/S0040-4020(00)01040-1

Cited by

  1. Mild and Efficient Silylcyanation of Aldehydes Catalyzed by Zirconium Complex. vol.36, pp.25, 2005, https://doi.org/10.1002/chin.200525033
  2. Enantioselective cyanosilylation of aldehydes catalyzed by Mn(salen) complex/triphenyl phosphine oxide vol.21, pp.9, 2007, https://doi.org/10.1002/aoc.1284