동의생리병리학회지 (Journal of Physiology & Pathology in Korean Medicine)

  • 제18권3호
  • /
  • Pages.792-796
  • /
  • 2004
  • /
  • 1738-7698(pISSN)
  • /
  • 2288-2529(eISSN)
대한동의생리학회·한의병리학회 ( The Physiological Society of Korean Medicine and The Society of Pathology in Korean Medicine)
권호 표지

창이자로부터 항산화 유효 성분의 분리

Isolation of Antioxidants from the Seeds of Xanthium strumarium

  • 이윤미 (원광대학교 한의학전문대학원 한약자원개발학과) ;
  • 강대길 (원광대학교 한의학전문대학원 한약자원개발학과) ;
  • 김명규 (원광대학교 한의학전문대학원 한약자원개발학과) ;
  • 최덕호 (원광대학교 한의학전문대학원 한약자원개발학과) ;
  • 이호섭 (원광대학교 한의학전문대학원 한약자원개발학과)
  • Lee Yun Mi (Department of Herbal Resources, Professional Graduate School of Oriental Medicine, Wonkwang University) ;
  • Kang Dae Gill (Department of Herbal Resources, Professional Graduate School of Oriental Medicine, Wonkwang University) ;
  • Kim Myung Gyu (Department of Herbal Resources, Professional Graduate School of Oriental Medicine, Wonkwang University) ;
  • Choi Deok Ho (Department of Herbal Resources, Professional Graduate School of Oriental Medicine, Wonkwang University) ;
  • Lee Ho-Sub (Department of Herbal Resources, Professional Graduate School of Oriental Medicine, Wonkwang University)
  • 발행 : 2004.06.01
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초록

In the courses of in vitro screening for the antioxidant effect of the various extracts from medicinal plants, n-BuOH soluble extract of the seeds of Xanthium strumarium was found to exhibit distinctive antioxidant activity. Further purifications of this extract as guided by in vitro antioxidant assay afforded caffeic acid and 3,5-di-O-caffeoyl quinic acid, which scavenged 1, 1-diphenyl-2-picrylhydrazyl (DPPH) radical in a dose-dependent manner of which IC50 values were 23.4 μg/ml (132.9 μM) and 29.8 μg/ml (57.9 μM), respectively.

키워드

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