Journal of Physiology & Pathology in Korean Medicine (동의생리병리학회지)

The Physiological Society of Korean Medicine and The Society of Pathology in Korean Medicine (대한동의생리학회·한의병리학회)
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Effects of In Vitro Synergism of Eunkyo-san and Rufloxacin against 9 Strains of Aerobic Gram(+) Bacteria

은교산과 Rufloxacin 병용이 호기성 Gram(+) 세균주에 대한 시험관내 항균력에 미치는 영향

  • Shin Ho Pill (Division of Respiratory System, College of Oriental Medicine, Daegu Haany University) ;
  • Jeon Kwi Ok (Division of Respiratory System, College of Oriental Medicine, Daegu Haany University) ;
  • Park Mee Yeon (Division of Respiratory System, College of Oriental Medicine, Daegu Haany University) ;
  • Kim Dae Jun (Division of Respiratory System, College of Oriental Medicine, Daegu Haany University) ;
  • Choi Hae Yun (Division of Respiratory System, College of Oriental Medicine, Daegu Haany University) ;
  • Kim Jong Dae (Division of Respiratory System, College of Oriental Medicine, Daegu Haany University)
  • 신호필 (대구한의대 한의학과 폐계내과학교실) ;
  • 전귀옥 (대구한의대 한의학과 폐계내과학교실) ;
  • 박미연 (대구한의대 한의학과 폐계내과학교실) ;
  • 김대준 (대구한의대 한의학과 폐계내과학교실) ;
  • 최해윤 (대구한의대 한의학과 폐계내과학교실) ;
  • 김종대 (대구한의대 한의학과 폐계내과학교실)
  • Published : 2004.12.01
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Abstract

In order to evaluate the in vitro synergic effect of Eunkyo-san, with quinolone antibiotics, rufloxacin (RUFX), the minimal inhibitory concentration (MIC), MIC50 and MIC90 of single use of quinolones and concomitant treatment with Eunkyo-san against 9 strains of aerobic gram positive bacteria. The obtained results were as follows : In the case of aerobic gram positive bacteria, the MIC, MIC50 and MIC90 against Staphylococcus aureus, Staphylococcus aureus smith, Staphylococcus epidermidis, Staphylococcus pyogens, Streptococcus pneumoniae Type Ⅰ, Type Ⅱ and Type Ⅲ was significantly decreased in concomitant treated groups with Eunkyo-san compared to those of single treated groups of RUFX, respectively. However, no significant changes were demonstrated against Bacillus subtilis and Enterococcus faecalis. In conclusion, the in vitro antibacterial activity of RUFX were increased against some strains of aerobic gram positive strains, especially, pneumococcus such as Staphylococcus and Streptococcus by concomitant use of Eunkyo-san.

Keywords

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