Journal of Physiology & Pathology in Korean Medicine (동의생리병리학회지)

The Physiological Society of Korean Medicine and The Society of Pathology in Korean Medicine (대한동의생리학회·한의병리학회)
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Effects of Gamichihyo-san and Gamiijung-tang on Airway Mucus Secretion

가미치효산 및 가미이중탕이 기도 객담 분비에 미치는 영향

  • Ryu In Sun (Department of Internal Medicine, College of Oriental Medicine, Daejeon University) ;
  • Kim Yoon Sik (Department of Internal Medicine, College of Oriental Medicine, Daejeon University) ;
  • Seol In Chan (Department of Internal Medicine, College of Oriental Medicine, Daejeon University)
  • 류인선 (대전대학교 부속한방병원 내과학교실) ;
  • 김윤식 (대전대학교 부속한방병원 내과학교실) ;
  • 설인찬 (대전대학교 부속한방병원 내과학교실)
  • Published : 2004.12.01
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Abstract

This study was done to investigate the effects of Gamichihyo-san and Gamiijung-tang on airway mucus secretion. After administer Gamichihyo-san(GCHS) and Gamiijung-tang(GIJT) extract to Golden Syrian Hamster for 8-10 weeks, we examined mucin release from cultured hamster tracheal surface epithelial(HTSE) cells. Following results were obtained; GCHG significantly stimulated mucin release from cultured HTSE cells, with minute cytotoxicity GIJT did not affect mucin release and have no cytotoxicity; GCHG and GIJT did not affect contractility of isolated tracheal smooth muscle. These results suggest that Gamichihyo-san might be usefully applied for airway mucus secretion.

Keywords

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